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Henkel Phenion Model Allows 3D Raw Material Testing

August 14, 2018 | Contact Author | By: Brooke Schleehauf
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Keywords: Henkel | Phenion Full Thickness Skin Model | Phenion | 3D Skin Comet Assay | skin testing | 3D skin testing | Henkel testing | Heinrich Heine University | in vitro testing | cosmetic testing | skin test | epidermis

Abstract: The model can be utilized in Henkel's 3D Skin Comet Assay to investigate the potential genotoxicity of raw materials.

  • Phenion Full-Thickness Skin Model
  • Phenion Full-Thickness Skin Model
    Separate cultivation of Phenion Full-Thickness Skin Models during chemical exposure.
  • Phenion Full-Thickness Skin Model
    Cultivation of Phenion Full-Thickness Skin Models

Henkel’s Phenion Full-Thickness Skin Model is now available to assess raw material safety; the model also is intended for use in dermatology and cosmetic science research.

Phenion models resemble human native skin in a 3D environment; they consist of a fully differentiated epidermis and the underlying dermis, with a collagen-based connective tissue. To create the company’s in vitro 3D Skin Comet Assay, the model was combined with an established procedure to test for the genotoxicity of raw materials.

Henkel recently worked with Heinrich Heine University to standardize the manufacturing of the model, allowing for quality control practices.

"Inventing innovative products require reliable test methods. Therefore, we at Henkel are engaged in developing new testing methods that allow us to assess the safety of ingredients," said Dirk Petersohn, Ph.D., director of Biological & Clinical Research, Henkel, in a press release.