
Remastered Fragments™: A New Era of Biotech-Driven, Sustainable Protein Fragments
LipoTrue introduces Fragments remastered™, a cutting-edge line of cosmetic actives that fuses biotechnology with sustainability. Using transient gene expression in wild plants cultivated through vertical farming, this innovation delivers biomimetic protein fragments with high efficacy, precision, and environmental responsibility.
Biotech Meets Performance
These fragments are produced by inserting synthetic human genes into wild plant systems, which act as biofactories. The result is a new generation of functional, protein-like molecules that replicate human proteins with exceptional fidelity, including crucial post-translational modifications. This ensures that the fragments behave like their native counterparts within the skin.
The technology creates a modular, animal-free, and sustainable platform for developing next-generation actives.
Col-Frag remastered™: Rethinking Collagen Type I
Col-Frag remastered™ is a biomimetic fragment of human collagen type I, synthesized in plants through vertical farming. Unlike hydrolyzed collagen or peptides, this fragment delivers the specific sequence required to stimulate collagen biosynthesis and rebuild dermal structure.
It carries essential hydroxylations for full biological activity. Clinically proven, it outperformed Ascorbyl Glucoside in reducing wrinkles, tightening skin, and enhancing brightness. It also helps delay skin aging by supporting both dermal and epidermal integrity.
Col-4-Frag remastered™: Strengthening the DEJ
This fragment targets collagen IV, a key structural protein at the dermo-epidermal junction (DEJ). Col-4-Frag remastered™ supports collagen IV synthesis and interacts with anchoring proteins such as perlecan and collagen VII.
By reinforcing the DEJ, it improves cell adhesion, nutrient exchange, and dermal-epidermal cohesion. Clinically, it reduces dark spots and wrinkles, especially in delicate areas like the face and neckline.
Frag-Brillin remastered™: Boosting Elasticity Through Cellasticity
Frag-Brillin remastered™ focuses on fibrillin-1, essential for forming elastic microfibrils. With age, the skin loses its remodeling ability due to reduced cellular contractility. This fragment introduces the concept of cellasticity— the cell’s capacity to contract, stretch, and reorganize.
By stimulating fibrillin and elastic fiber formation, it enhances skin elasticity, firmness, and reduces wrinkles both on the face and body.
Sustainability at Its Core
All Fragments remastered™ are produced in a closed vertical farming system with:
- LED lighting for optimal protein expression
- No pesticides
- Biodegradable pots and soil recycling
- Renewable energy via solar panels
- Water recycling and resource optimization
This ensures a low environmental footprint while delivering high-performance skincare solutions.
A New Paradigm in Cosmetics
The Fragments remastered™ line marks a new category of active ingredients that merge scientific innovation with ethical responsibility. With Col-Frag remastered™, Col-4-Frag remastered™, and Frag-Brillin remastered™, LipoTrue delivers smart, sustainable, and highly effective tools for modern skincare needs.
Welcome to the future of cosmetics—fragmented, remastered, and reimagined.
For more information visit www.lipotrue.com or contact [email protected]
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