What physico-chemical properties do your formulas have? Will they remain stable? Do their viscosities, performance, etc., endure changes in pH or temperature?
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Physico-chemical property analysis is one way to predict their behaviors. As ingredient supplier Seppic explains on its website, "physico-chemical tests are used to characterize properties, anticipate behavior in formulation and measure performance ... under real usage conditions." The company adds that such tests also help to optimize the ingredient or formula structure, guiding the product developer to make adjustments that achieve the functionality and behavior desired by end users.
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More specifically, as Calixto and Maia Campos report, rheological, texture and sensory analyses are important to understanding the behavior and stability of formulations. Cheung, et al., even proposed the creation of products based on their constituents and microstructure, rather than traditional trial-and-error and screening formula variations in a combinatorial manner. "In doing so, understanding of the physical phenomena that control the product performance forms the basis for rationalizing the development process," the authors wrote.
Taking this to the next level is dynamic streaming potential. According Anton Paar, a company with extensive expertise in this area, the dynamic streaming potential phenomenon enables "real-time monitoring of interactions between solutes and solid surfaces. This method does not primarily focus on static processes, but emphasizes temporal changes, focusing on phenomena such as the accumulation of dissolved substances and the effects of adsorption and desorption on solid surfaces."
Anton Paar explains how it all works in a new webcast, "Dynamic Streaming Potential: An Analytical Contribution to Formulation Science." Join us on Thursday, Nov. 21, 2024, at 10:00 a.m. Eastern. Register now, it's free!
