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Young Beautiful Multiracial Girl Smiling Using Facial Skin Care

Modeling and Targeting Cell Communication, Senescence and Immunoevasion to Support Skin Longevity

The present work sought to develop in vitro models to study the mechanisms of key hallmarks of aging: cellular communication, senescence and immunoevasion. The models were then used to test the efficacy of natural actives targeting these mechanisms.

woman in red dress floating in water with algae

Microalgal Bio-retinoid: A Retinol Alternative to Gently Rewind Signs of Photoaging

This article compares the efficacy of a bio-retinoid from microalga with that of retinol and bakuchiol to reverse signs of photoaging in vitro. Its efficacy, safety and skin-soothing effects vs. retinol and bakuchiol are also explored in clinical trials.

Bee wax honey dipper spray bottle

How Bee-friendly Aqueous Propolis ‘Sticks it’ to Microbiota Dysbiosis, Skin Conditions

An aqueous, or white propolis, extract was tested in vitro and shown to affect microbiota connected with skin conditions. In vivo trials also demonstrated the ingredient’s safety and efficacy in reducing skin discomfort, dryness and body odor.

woman hiking mountains backpack using sunscreen

2025 Will See Faster, More Ethical and Accurate SPF Testing: ISO Approves Two New Methods

In December 2024, the ISO gave its long-awaited final approval of two SPF test methods that experts say are more ethical, economical and accurate than current approaches. One in particular is also reportedly faster, reducing analysis from weeks to days.

'Health and wellness motivations are underpinning this consumer desire, with 46% of U.S. consumers citing moderate or extreme concern over their skin health in 2024, up from 38% in 2023...'

How Dermocosmetics Are Driving the Beauty Revolution: Beauty Accelerate 2025 Preview

"Euromonitor data shows that, since 2019, more U.S. consumers are looking for skin care features like dermatologist-tested, specific ingredients and clinical formulations, motivated by an underlying demand for safety, transparency and healthy living..."

Ron Robinson, BeautyStat

⚠️BeautyStat's Ron Robinson to Explore Science-based Beauty at Beauty Accelerate 2025 👀

Ron Robinson, cosmetic chemist, CEO and founder of BeautyStat, will join the Beauty Accelerate 2025 lineup, participating in the expert panel discussion on: Dermocosmetics and Science-backed Beauty. Register now.

beautiful Asian woman with radiant glowing skin

Testing Tactics in Skin: Evaluating Radiance and Texture

Hydrated, even-toned skin with a natural glow, all indicators of health, has gained popularity in the last decade. This article explores the meaning of skin radiance, its relationship to texture and various ways to measure this desired attribute.

For desirable hair styles, both stiffness and flexibility are necessary – but the two properties are generally considered incompatible.

Isomalto-oligosaccharides Naturally Balance ‘Stiffness’ with Flexibility for Hair Styling Benefits

This article describes enzymatically controlled naturally derived isomalto-oligosaccharides. It demonstrates how they balance stiffness and flexibility to maintain hair styles, as well as reduce the need for synthetic setting polymers.

After 14 days, M. cochinchinensis extract improved stinging, irritation, itch and discomfort by 67%, 100%, 91% and 100%, respectively.

Holistically Derailing the Sensitive Scalp ‘Rollercoaster’

A Maclura cochinchinensis extract was developed to provide holistic relief for sensitive scalps by derailing multiple interconnected aspects of this “rollercoaster” condition. The active’s efficacy was tested in vitro and in vivo as described here.

To provide a natural solution for sensitive skin, a hyperbranched dextrin was developed and tested for soothing and protective effects. The absence of adverse effects on the microbiome also was assessed by a third party, with promising results.

Hyperbranched Dextrin for Soothing, Microbiome-friendly Skin Care

To provide a natural solution for sensitive skin, a hyperbranched dextrin was developed and tested for soothing and protective effects. The absence of adverse effects on the microbiome also was assessed by a third party, with promising results.

Transdermal microneedle patches enable active ingredients to bypass the slow diffusional process across the stratum corneum’s barrier to reach directly into the deeper skin layers.

How Dissolving HA Microneedles Change Before/After Application

Dissolvable microneedles have gained popularity to overcome the skin barrier and deliver actives. Here, SEM was used to evaluate changes that occur to microneedles upon application. The results could provide claims and regulatory classification insights.

The present study examined the effects of commercially available jojoba esters in liquid, natural jojoba-like form in three studies measuring irritation mitigation, skin hydration and soothing properties.

Jojoba Oil Esters Ease Inflammation, Sensitivity and Water Loss from Skin and the Environment

Water scarcity has become a major concern and jojoba is known to flourish under controlled low water conditions. As such, jojoba wax esters were explored for skin care to reduce inflammation and sensitivity and to provide hydration over a 24-hr period.

Xylyx Bio Matrikynes Exhibits Clinical Anti-aging, Barrier Repair Efficacy

The ingredient is based on matrikines, whose intrinsic bioactivity have been shown to activate regenerative mechanisms that can drive tissue repair, the company reports.

Learn more about RNA sequencing and how it benefits claims support in this exclusive podcast, sponsored by Genemarkers. Register now to listen; it's free.

[podcast] How RNA Sequencing Advances Claims Support

RNA sequencing is a newer, more dynamic approach than DNA sequencing to measure the effects of ingredients and products on skin. Rishabh Kala, Ph.D., of Genemarkers, explains its capabilities in this sponsored podcast. Listen now; it's free.

Using an oil blotting film to collect facial sebum, Kao can apply skin surface lipids-RNA monitoring technology to 'infer' skin and physical conditions such as pediatric atopic dermatitis and Parkinson's disease.

Kao's New Infant Sebum Testing Protocol Can Flag Atopic Dermatitis, Parkinson's Disease

The move is the start of Kao's expansion into health testing services.

In evaluating how different solvents may affect the rheology of personal care formulas, it is helpful to consider that different formulation types have distinct relationships between viscosity and elasticity depending on the factors generating their elastic properties.

How Natural Butylene Glycol Advances Market and Rheology Dynamics

Demand for sustainable ingredients in cosmetics and personal care is well-known. Here, a sustainable natural butylene glycol is described to advance this trend and its effects on viscosity and elasticity are assessed in five test formulas.

Like other markets, efficacy testing, including for cosmetics, is projected to have a substantial increase in revenue by 2027, largely due to pharmaceuticals and biotechnology making constant advancements in relation to public views and the pandemic.

Efficacy Testing Market Worth $423 Million by 2027

Like other markets, efficacy testing, including for cosmetics, is projected to substantially increase in revenue by 2027, largely due to pharmaceuticals and biotechnology making constant advancements in relation to public views and the pandemic.

The authors believe that adding the properties of a wide range of commercial sunscreens to the system database will increase the rate of appropriate sunscreen usage by customers.

AmorePacific, Hanyang Univ. Dynamically Visualize UV Dose on SPF-protected Skin

Work by AmorePacific and Hanyang University, Seoul, published in Skin Research & Technology, reveals a dynamic approach to visualize UV dose based on MED, weather, outdoor activity, etc., on SPF-protected skin.