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160 Results
Section: Testing
Claims/Labeling
China Cracks Down on Misleading Cosmetic Claims—Here's How to Comply
With tighter cosmetic regulations in China, the country is watching for and subduing misleading or false product claims. To avoid penalties and ensure compliance, regulatory consulting firm ChemLinked offers solutions.
Tech/Equipment/Services
Stroke of Genius: Successive Combing Force Yields Realistic Conditioning Results
Combing tests are widely used to characterize the conditioning performance of products at one snapshot in time. A successive combing force device was designed to more realistically simulate the entire shampooing and conditioning process. Here, the authors put it to the test.
Literature/Data
[updated] How to Ensure Cleansers Comply with Growing 1,4-Dioxane Regulations
A review in the
Journal of Surfactants and Detergents
explored means of measuring 1,4-dioxane levels in cleansers in order to comply with increasing ppm restrictions set by U.S. states. In this update, industry expert Tony O'Lenick adds context.
Efficacy
Aubergine Mutes TRPV1 and Boosts TRPV-3 and -4 to Reinforce and Comfort Skin
While the causes of sensitive skin are not confirmed, they most likely are due to a neurogenic inflammation after the enhanced activation of sensory proteins in keratinocytes. The present work tested the ability of a
Solanum melongena
(aubergine) cell culture extract to inhibit sensory mediators of discomfort and activate barrier-boosting pathways.
Tech/Equipment/Services
Is Your Microbiology Lab FDA-compliant? Part I: Personnel, Facilities and Equipment
This two-part article provides an overview of areas relevant to the U.S. Food and Drug Administration’s (FDA’s) inspection of cosmetic microbiology laboratories. Part II will appear in our July 2018 edition.
Efficacy
Targeting Texture: Adapted Combing Test to Assess Curly Hair Product Efficacy
Changes in hair styling practices have increased the demand for hair products to maintain naturally textured hair condition and health. In relation, the current work aimed to develop test methods using naturally textured hair to assess products and ingredients specified for these hair types.
Sensory
'Zapping' Sensitive Skin: Capsaicin Tests Show
Embelia concinna
Comforts Irritation
In previous work, a flavonoid-titrated active ingredient based on
Embelia concinna
was shown in vitro to calm and soothe sensory neurons stimulated with capsaicin. Here, those results are confirmed in vivo using a capsaicin stinging test with human volunteers.
Animal Alternatives
3D Skin Substrate Meets Speed, Complexity and ECM-based Research Needs
Researchers from the University School of Dental Medicine in Boston have published on a 3D skin equivalent model with high throughput potential and greater cellular complexity originating from human ECM.
Efficacy
Reduction of skin stress by CBD products: Aiming high above the competition
The use of cannabinoid products is growing in popularity. Formulate with cannabinoids confidently with effective technology development strategy from Eurofins – download a free brochure on CBD testing for safety and compliance.
Method/Process
Modeling and Targeting Cell Communication, Senescence and Immunoevasion to Support Skin Longevity
The present work sought to develop in vitro models to study the mechanisms of key hallmarks of aging: cellular communication, senescence and immunoevasion. The models were then used to test the efficacy of natural actives targeting these mechanisms.
Efficacy
[podcast] Author Commentary: Fabio Apone, Ph.D., on Cold Stress Skin Damage
The mechanisms of cold stress damage in skin are a new focus for cosmetics research. In his January 2018 article, Fabio Apone, Ph.D., explains these mechanisms; in relation, in this Author Commentary podcast, he shares what drove his team’s interest in this area and the next steps. Listen now!
Sensory
Author Commentary: John Jiménez and Mauricio Guzman Alonzo on Synesthesia in Cosmetics
Most everyone knows what it's like to be a consumer. More recently, product developers have been tapping into this experience to evoke emotional connections in consumers. John Jiménez and Mauricio Guzman Alonzo, authors in our latest issue, have been leading this charge for cosmetics development. Here, they share their insights.
Animal Alternatives
Canada Commits to End Animal Tox Testing While MoCRA Misses the Mark
Bill S-5 in Canada has passed with royal assent to end animal testing for chemical toxicity; cosmetics are expected to be next. Meanwhile, MoCRA in the U.S. missed the chance to address this major industry issue, one source critiques.
Animal Alternatives
Public Comments Requested for Development of NICEATM-ICCVAM 2013-2017 Five-Year Plan
NIEHS and NICEATM invite public comments that can be considered by the ICCVAM and the agencies' program offices in updating the NICEATM-ICCVAM 2008-2012 Five-Year Plan to develop the 2013-2017 Five-Year Plan.
Method/Process
Clinical Evaluation of a Zinc- and Copper-based Eye Area Anti-aging Complex
A zinc and copper complex generating biomimetic electricity on a physiological level is shown here to improve the signs of photoaging in preclinical and clinical studies. This complex was applied to the eye area to confirm its efficacy as an anti-aging treatment option with good skin tolerance.
Sensory
Wellness by Design: Positive Comparison Patterns to Engage Latin American Consumers Through Fragrance
A well-crafted fragrance that aligns with sociocultural values can inspire positive emotions in consumers. To achieve this, Positive Comparison Patterns (PCPs) in neuroscience are introduced here and used to elicit positive scent experiences in Latin American women.
Tech/Equipment/Services
Is Your Microbiology Lab FDA-compliant? Part II: Cultures, Growth Media, Reagents and Testing
This two-part article provides an overview of areas relevant to the U.S. Food and Drug Administration’s (FDA’s) inspection of cosmetic microbiology laboratories. Part 1 covered personnel, facilities and equipment, test materials and procedures, and documentation. Part 2 addresses microbial cultures and growth media, biochemical reagents, test procedures and more.
Method/Process
Comparison of Age Determination by Three Evaluation Methods: Self-assessment, Expert Grader and Naïve Grader
This exploratory study investigates how consumers perceive age, using objective and subjective approaches. Results of this study suggest that when a subjective approach is implemented for age determination, subjects affix their emotions to the evaluation. The reverse logic was applicable for the expert and naïve grader methods, as grader results appeared more neutral than the self-assessment.
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