Mature and Immature Corneocyte Detection Force Distance Curves vs. Microfluorometry

Corneocyte maturity plays a crucial role in dermatology and cosmetic science because immature corneocytes in the stratum corneum (SC) can cause impaired barrier properties. This poses a threat to overall health, since it is the outermost layers of the SC that protect the body from invasion by pathogens and viruses.1, 4 Interestingly, studying corneocyte maturity has enabled dermatologists to determine there are no differences in corneocyte maturity across different racial groups. Further, a causal relationship has been found between excessive amounts of immature corneocytes and dry skin in all ethnic groups.2

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