To avoid the acute irritation and dryness that a sincle occlusive surfactant application (24-h) patch tes4t may cause, and to more realistically approximate actual consumer use, an open assay model was chosen to define subclinical, non-erthematous irritation in the stratum corneum. The model evaluates irritation by using clinical and instrumental techniques, as welll as squamometry measurements obtained from skin strippings.
Open Assay Models (Washing) for Evaluating Subclinical Irritant Dermatitis
June 26, 2009
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4/3/2020, Uli Osterwalder, Sun Protection Facilitator (SPF) GmbH, Basel, Switzerland; Steffen Uhlig, Ph.D., and Bertrand Colson, QuoData Quality and Statistics GmbH, Berlin and Dresden, Germany; Jürgen Vollhardt, Ph.D., DSM Nutritional Products Ltd., Switzerland
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