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Type: Article

Section: Testing > Animal Alternatives

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Expert Opinions: Color Pause*

Featuring insights on cruelty-free, inclusivity, sustainable, renewable and more, this month's collection of "Expert Opinions" is all about the pause on color cosmetics. Click through to the digital magazine for the complete article.

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Strat-M® Membrane for Transdermal Diffusion Testing – FREE Sample

Strat-M® membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin and is an alternative to animal testing. Learn more about this innovative technology and request a free sample.

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Making Moves Toward an Animal Testing-free Future

I think the cosmetics industry will agree: we want to see animal testing phased out in our lifetimes. Not only for ethical reasons, but because these methods are much less relevant than today's alternatives. The good news is worldwide efforts are getting us there; following are recent examples.

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Australian Chemical Reform in Action

The Australian government released a proposal to change its national chemical notification scheme earlier this year, which will include a ban on animal testing. Interestingly, it allows for risk-based regulation.

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Micropatterning Plus High Content Assay for Skin Research, Explained in Brief

What can high content screening, combined with micropatterning, tell researchers about the efficacy of a cosmetic active? Better yet, what are these techniques? Here, Luc Selig, Ph.D., CEO of CYTOO, explains.

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Is This the Tail End of Animal Testing for Cosmetics and Personal Care?

With awareness of animal testing rising--due in part to conversations via social media and an influx of companies granting "cruelty-free" wishes--brands that are slow to omit animal testing may see consumers opting for other products they know have never been tested on animals.

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A Century of Cosmetic Regulation [Timeline]

The modern FDA began to take shape after color additive misuse came to light in The Jungle. Personal care regulation has come a long way in the century that followed—Click through to learn more.

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Is it Toxic? EU Mandate, Part 10: Safety

For each cosmetic product placed on the EU market, a safety evaluation must be performed. This includes a review of the toxicological profile of its ingredients, with a particular focus on genotoxicity. This mandate is described here.

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3 Skin Sensitization Tests to Meet the EU Mandate

The EU Cosmetics Regulation requires skin sensitization to be determined through non-animal methods. Here, the pathways for skin sensitization are reviewed, three non-animal tests are described in brief, and their combination with one another, followed by human assessment, are explored.

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CTPA on Brexit: 'Refrain from Hasty Actions'

While the BBC recently explained "all that citizens need to know" about the U.K. departure from the EU, the cosmetics industry should know the implications, too. Emma Meredith, Ph.D., of the UK-based CTPA, explains what is and isn't known.

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Gauging Cosmetic Safety in a Post-Animal Testing World

The testing of cosmetic and personal care products on animals has become widely perceived as a vile, often cruel and inhumane practice. Many countries have either banned its use or have pending legislation to do so. The dilemma this leaves is creating reliable methods to test products for safety and quality.

A Novel Explant Model for Skin Delivery Assessment

Mechanisms implied in the skin absorption process and the role of cutaneous metabolism are of increasing interest to cosmetics research. In the present paper, the authors demonstrate how an experimental human skin explant model exhibiting great barrier function and metabolic activities can provide an understanding of what happens to cosmetic actives when they are topically applied.

Demystifying Cosmetic Science for Consumers

Cosmetic scientists know the headaches of alarmist groups and junk science. They reformulate products pulled from shelves due to mistruths from would-be "experts." Joe Schwarcz, PhD, of McGill University will explore why there is a need to demystify cosmetic science during the Cosmetics & Toiletries Summit.

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Non-animal Transdermal Diffusion Model Testing for Cosmetic Actives and Formulations

Experience the unmatched predictability of Strat-M membrane—a synthetic, non-animal based model* for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

A Synthetic Tissue-based In vitro Ocular Irritation Assay

The testing of personal care products for ocular irritancy ensures their safety, proper labeling and consumer satisfaction. In relation, there is a current demand for animal-alternative tests. Thus, described here is a method using synthetic tissue to test for mild, moderate and severe ocular irritation, including data validating this method as an effective means to screen products.

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Alternatives to Animal Testing: A Review of Trends and Perspectives

Alternative test methods have the potential to reduce animal testing; however, the extent to which in vitro methods can be replaced is questionable. This article summarizes validated alternatives to test the safety of cosmetic ingredients. It also illustrates how great a challenge it is to devise a proper alternative method.

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Non-animal Transdermal Diffusion Model Testing for Cosmetic Actives and Formulations

Experience the unmatched predictability of Strat-M membrane—a synthetic, non-animal based model* for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Compass—Best Foot Forward

From an insider’s view, safety testing is an assumed step in the development of any product on the market. This puts the pressure on analytical and quality control efforts behind the scenes to ensure that ingredients and products meet or exceed expectations. In doing so, theoretically, no one else has to give it a second thought. For those who must give it considerable thought, this edition features two articles on testing, among other topics.

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