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160 Results
Section: Testing
Animal Alternatives
BASF and Givaudan Develop First OECD-Approved Animal Test Alternatives
The OECD has, for the first time, approved a non-animal strategy to assess skin sensitization based on three tests. In addition, the Kinetic Direct Peptide Reactivity Assay was approved to predict the intensity of reactions. All tests are the results of BASF/Givaudan joint efforts.
Literature/Data
Givaudan Active Beauty Leads the Way in Skin Microbiome Research
At Givaudan, innovation is in our DNA: we thrive on the challenge of constantly pushing boundaries to develop new ideas and enhance existing concepts. In a bid to take our Active Beauty cosmetic ingredients to the next level, seven years ago we launched a pioneering research project into the relationship between the human microbiome and our health, beauty and well-being. Discover our dedicated video and be conquered.
Testing
Omni Antioxidant: Acetyl Zingerone Scavenges/Quenches Reactive Species, Selectively Chelates Iron
Daily exposure to environmental stress keeps skin under a persistent burden from excess ROS. This drives premature skin aging. The present article explores the multiple effects of a single ingredient, acetyl zingerone, to proactively manage excess ROS production via chemical and physical paths.
Method/Process
Bio + Chemo Guidance Uncover New Benefits in Known Naturals:
Murraya Koenigii
Extract Case Study
Murraya koenigii
extracts derived via various techniques were compared. One developed through chem- and bio-guidance paired with a natural deep eutectic technology uncovered lesser-known efficacies, leading to a natural active to boost elastin synthesis.
People
Inolex Welcomes Kevin Gallagher to Board
Inolex appointed Kevin Gallagher as a non-executive member of its board of directors.
Tech/Equipment/Services
Preclinical Testing Platform Launched on Skinobs.com
Skinobs.com offers its latest search platform, this one dedicated to preclinical testing. Here, researchers can identify services and information about the preclinical test methods their projects require; from general testing and claims support and testing implements.
People
Akott Welcomes Mohamed Essawi to Expand Business
Akott Evolution, an international manufacturer in research and development of active ingredients, has announced a new technical sales coordinator for the EMEA region. The new hire brings knowledge of the global market to benefit the company.
Animal Alternatives
ICCVAM Recommends Non-animal Endocrine Disruptor Screening
The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has recommended a non-animal test method to identify estrogen agonist and antagonist activity. In addition to recommending the test, ICCVAM also found the method to provide a number of benefits over the method currently employed in the United States.
Sensory
Falling Ball Viscometer for Newtonian Fluid Measurement
Brookfield Engineering celebrates its 75th anniversary with the introduction of the Falling Ball Viscometer, an instrument to assess the dynamic viscosity of transparent Newtonian fluids.
Literature/Data
VIDEO: Gallagher Notes Innovation, Sustainability, Among Accomplishments
In a recent exclusive interview with C&T, Kevin Gallagher, Croda’s retiring president of personal care/actives, spoke about some of the significant accomplishments of his long career with Croda. See what he talked about with C&T’s Rachel Grabenhofer.
Regional
[updated] FDA Oversight Becomes Closer to Reality for US Cosmetics
According to the bill's authors, it is supported by the leading cosmetic manufacturers and would give the FDA unprecedented authority.
Editor's note: This report now includes CIR commentary.
Method/Process
ICCVAM Recommends Ocular Safety Tests for Cosmetics and Other Products
Four test method evaluation reports are now available from ICCVAM that provide recommendations for performing eye safety testing more humanely, and for developing and using non-animal test methods and strategies. Among these reports, ICVAAM has recommended that a cytosensor microphysiometer (CM) test method may be used to screen surfactant-containing formulations such as personal care products for the ability to cause permanent or severe eye injuries.
Sun Protection
7 Years in the Making: CE Recommends In vitro SPF Double Plate Test Method
"... No in vitro method had [previously] advanced to the stage that CE could recommend it. So those who did not want to use an in vivo method could use any ... unvalidated method; this should no longer be the case."
SPF/Sun
Science Exposed—What Should the Minimum Recommended SPF Be to Avoid Sunburn?
“Science Exposed” is a new column aimed at digging into industry controversies to strip them down to the scientific facts. Here, sun protection expert Brian Diffey, PhD DSc, critiques the current SPF test method.
Literature/Data
Derms Need to Think Twice About OTC Recommendations, Study Shows
Consumers faced with compromised skin often look to their dermatologists for over-the-counter (OTC) product advice, to help keep costs (and allergens) in check. But findings from a new product review suggest derms need a second look at what they're recommending.
Animal Alternatives
'Ordinary' French Cosmetics Become the First to Bypass China’s Animal Testing Mandate
France has become the first country in the EU to export “ordinary” cosmetics to China without testing on animals.
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