Current Issue cover

Givaudan Chronoglow Combines AI and Epigenetics for Skin Radiance

Contact Author Michele Behrens
Fill out my online form.
  • Chronoglow combines AI and biomimetic epigenetics to improve skin appearance.
  • Eau de Radiance is formulated with Chronoglow to impart a glowing veil for skin regeneration.
  • Chronoglow is a natural active for the skin to reportedly reverse the effects of aging.


Givaudan Active Beauty presents Chronoglow, an active ingredient made by green fractionation and boosted by Artificial Intelligence (AI) to mimic botanical epigenetic mechanisms for skin care benefits.

Related: Givaudan Repairs and Restores Skin Barrier with Upcycled Omegablue

Created from Haberlea rhodopensis, also known as the resurrection plant, Chronoglow is a natural active for the skin designed to reverse the effects of aging and improve its radiance. According to Givaudan, the ingredient rejuvenates the skin at different cellular levels, from epigenetics to protein expression, and protects cells against senescence and oxidation.

The company’s researchers used AI to better represent the clinical results and demonstrate the visual benefits of Chronoglow. The active reportedly enhances skin firmness and provides three dimensions of glow:

  • Elasticity: After two weeks of use, Chronoglow improved elasticity by up to 8.9%, which was shown to be 3× better than the placebo. This positive impact on the skin elasticity was shown during the whole duration of the clinical test, with an increase of up to 15.3% after two months.
  • Luminosity: This factor improved by up to 3.8% after four weeks and up to 6.4% after two months.
  • Radiance: After two weeks, radiance was improved up to 6.1% and up to 12.5% after two months, which performed 4× better than the placebo.

Previously: Givaudan Unveils Nootropics: 6 Botanical ‘Giants’

With this ingredient, experts crafted Eau de Radiance, a "glowing veil" prototype formulation to reportedly regenerate the skin. A few drops of the liquid on the face is said to rejuvenate and illuminate skin tone.

Haberlea rhodopensis is an Ice Age plant that has survived extreme climate conditions thanks to its epigenetic mechanisms of cellular survival,” noted Mathias Fleury, category manager of Givaudan Active Beauty. “We are now able to mimic and reproduce what the plant does in its cells in the skin. Chronoglow is therefore a 100% natural and sustainable powerful botanical ingredient, with exclusive benefits of well-aging and radiance.”

For more information, contact Givaudan Active Beauty.



Next image >