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220 Results
Section: Testing > Safety/Stability
Literature/Data
Researchers Develop Invertebrate Alternative In vivo Skin Corrosion Test
Work published in Environmental Pollution describes an invertebrate alternative in vivo skin corrosion test that reportedly is more sensitive to acids and alkalis than traditional skin models.
Method/Process
Testing the Safety and Efficacy of Multifunctional Personal Care Products, A Primer
Multifunctional products may offer solutions to consumer challenges but as the needs of consumers grow more complex, so do their safety and efficacy testing. This article provides a primer on these considerations.
Animal Alternatives
CTPA Convenes to Progress the Use and Regulatory Acceptance of Animal Testing Alternatives
The CTPA and the U.K. cosmetic industry wants to promote the use of new approach methodologies (NAMs) as alternatives to animal testing for these vital safety requirements under other chemicals legislation, especially UK Reach.
Animal Alternatives
Animal Aid Funds XCellR8 for Animal-free Safety Testing
Animal-Aid has pledged £51k to accelerate the research, development and commercialization of acute toxicity tests by ethical safety testing laboratory XCellR8.
Safety/Stability
CIR Assesses Safety of
Rosa Centifolia
Derivatives in Cosmetics
The CIR reviewed the safety of
Rosa centifolia
-derived ingredients, most of which are reported to function as skin conditioning agents in cosmetic products; read on for the findings.
Regional
Hazard List, Harmonization, Toxicity Tests and O'Malley Appointment: ECHA Updates
This ECHA update includes one addition to the hazardous chemicals list, two proposals for harmonized classification/labeling (eugenol and tetrahydrofurfuryl methacrylate), advice for toxicity test dosing and the appointment of Shay O'Malley.
Safety/Stability
Analyze, Optimize: Ensuring Pollution Won’t ‘Get Under Your Skin’
Anti-adhesion, removability, anti-penetration and cleansing properties were assessed in steps, as described here, to optimize formulas for effective anti-pollution protection. An approach was designed to test cosmetic ingredients and formulas for their abilities to suppress the negative effects of pollution in skin.
Safety/Stability
Letter to Editor Questions Benzophenone Study; Author and Industry Expert Respond
A Letter to the Editor in
Chemical Research in Toxicology
points to flaws in a study gaining recent attention and calling for the removal of octocrylene-containing sunscreens from the market. The author responds; as does an additional industry expert, David Steinberg.
Safety/Stability
Toxicological Evaluation of Cosmetics: A Primer
A cosmetic toxicologist can provide a clear-eyed view of the potential hazards and quantifiable risks of a product based on its composition. This primer briefly explains how.
Safety/Stability
Research Reviews Non-penetrating Sunscreen Vehicles, Looks to Jojoba
Several "carriers for the future" were highlighted, such as lipid carriers, cyclodextrin derivatives, encapsulation approaches and non-penetrating sunscreens incorporating UV filters and jojoba oil conjugates.
Bath/Shower
SCCS on Methyl Salicylate: Safe Within Cosmetic Limits, Weak Sensitizer
The European Scientific Committee on Consumer Safety (SCCS) recently issued its preliminary Opinion on the safety of methyl salicylate.
Animal Alternatives
BASF and Givaudan Develop First OECD-Approved Animal Test Alternatives
The OECD has, for the first time, approved a non-animal strategy to assess skin sensitization based on three tests. In addition, the Kinetic Direct Peptide Reactivity Assay was approved to predict the intensity of reactions. All tests are the results of BASF/Givaudan joint efforts.
Color Cosmetics
Cosmetics Study Prompts Legislation to Ban PFAs
The authors concluded: "The cosmetic categories that had the highest percentage of high fluorine products were foundations (63%), eye products (58%), mascaras (47%) and lip products (55%)."
Organic/COSMOS
Confounding Labels: One ‘Natural’ = 100+ ‘Chemicals’
As most formulators are aware, creating a product with three or more botanicals in it means a final formula containing more than 200 chemicals. How is this better for skin? It's not, according to this commentary.
Anti-aging/Face
Mary Kay Blends Retinol with TRPV1 Antagonist for Non-irritating Efficacy
During the 2021 SID virtual meeting, Mary Kay Inc., shared work combining the efficacy of retinol with botanicals to reduce its irritation; the company also announced it will fund four research grants related to skin health.
Claims/Labeling
Concerns Over Charcoal Safety Raised in Crest Toothpaste Lawsuit
A class action lawsuit filed in New York alleges that P&G promoted the safety of its activated charcoal-containing Crest toothpaste despite expert opinions finding a lack of safety and efficacy substantiation.
Regional
FDA Cautions: Hair-smoothing Products Can Release Formaldehyde
The U.S. Food and Drug Administration recently released a statement warning users of the potential for hair-straightening products to release formaldehyde gas, a known carcinogen, during heat treatments.
Regional
900+ Hand Sanitizer Poisonings, Mexican Imports Put on FDA Alert
CBS News
recently reported 900+ Americans were accidentally poisoned by hand sanitizers in January 2021 alone. In relation, the FDA has placed an import alert on all Mexican sanitizers, which have been the source of multiple offenses.
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