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206 Results

Section: Testing > Safety/Stability

Echa Candidate List

Butylparaben Blacklisted as ECHA Substance of High Concern

The ECHA’s candidate list of substances of very high concern (SVHCs) now has 209 entries. The latest materials added include three that are identified as toxic to reproduction and one endocrine disruptor—butylparaben. The EU aims to phase these out.

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FDA Flags Eskbiochem Hand Sanitizers for Possible Methanol Content

The U.S. Food and Drug Administration has issued a warning statement to consumers over the use of Eskbiochem's hand sanitizers, which may contain methanol, i.e., wood alcohol.

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3D Skin Substrate Meets Speed, Complexity and ECM-based Research Needs

Researchers from the University School of Dental Medicine in Boston have published on a 3D skin equivalent model with high throughput potential and greater cellular complexity originating from human ECM.

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Arbonne Recalls Contaminated Shea Body Wash

Arbonne recently recalled certain lot numbers of its Shea Butter Body Wash, Gel Douche due to contamination by Pluralibacter gergoviae bacteria. This follows incidents reported for other products.

Echa Regulatory

ECHA Speeds Regulatory Action for Hazardous Chemicals

To speed up identifying and managing the risks of hazardous chemicals, ECHA is screening structurally similar substances in groups. Last year, the agency, together with national authorities, reviewed around 220 high-volume substances, of which 56% required more hazard data.

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ZnO Nanoparticles Penetrate but Only Under These Conditions

Zinc oxide (ZnO) nanoparticles are a major component in sunscreens but their ability to permeate skin has remained undetermined. Recent work in Applied Biomaterials identifies the conditions under which they penetrate—notably, not in their nano form as they exist in sunscreens.

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Do Nanomaterials Penetrate Skin? EUON Commissions Review Study

The EUON commissioned a literature review to explore the potential dermal absorption of nanomaterials. Results found the materials rarely penetrate intact skin, except for ionic silver, but a more standardized approach to testing is needed.

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GARDskin Provides Animal-free Way to Guard Skin

SenzaGen and XCellR8 have recently expanded its collaboration to offer GARDskin Animal Product-free, an animal-free skin sensitization assay safety assessment for chemicals in products.

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Standardizing Safety: ISO Validation and Sun Protection Tests

In addition, methods under review pertaining to sun protection are discussed. The ISO sets proposed standards and test methods for nearly every industry; its validation process is described here.

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SCCS Concludes DHA is Safe for Hair Dyes

The SCCS released its opinion on dihydroxyacetone (DHA; 1,3-dihydroxy-2-propanone) at a plenary meeting held on March 4, 2020: the ingredient is safe for use as a hair coloring ingredient in leave-on treatments, and in self-tanning lotions and face creams.

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FDA Issues Draft Guidance for Topical Drugs

Contact dermatitis from topical drugs and human safety are the topics in a recently issued guidance document made available by the FDA. Comments are sought through May 8, 2020.

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With Skin Sensitivity Up, SGS Has Tolerance Testing Down

In a market where skin sensitivity claims continue to rise, SGS proposes methods here to determine product safety for skin; one of which is a skin tolerance test, to which successful products are awarded an official "seal."

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What’s Your Environmental Impact?

Eurofins encourages consumers and formulators alike to monitor the environmental impact of cosmetic products. One way to achieve this is through an ecotoxicological test, which can pave the way for "green" products.

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Strat-M® Membrane for Transdermal Diffusion Testing – FREE Sample

Strat-M® membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin and is an alternative to animal testing. Learn more about this innovative technology and request a free sample.

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DevaCurl Slapped with Class-action Lawsuit

The Manhattan Federal court suit states various DevaCurl products have caused "scalp irritation, excessive shedding, hair loss, thinning, breakage and/or balding during normal use."

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Patch Testing, Irritation and Sensitization: Safety Testing in Cosmetics

An online exclusive by Anjali Salvi, Ph.D. about product safety and what needs to be done for consumers. Salvi discusses how regional conditions, intended use of the product and method of application can be a huge factor in determining product safety for consumers worldwide.

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Greenbrier International/Dollar Tree Flagged for Acne Pad Import Violations

FDA inspections revealed violations at multiple foreign manufacturers that supply acne pads and drugs to the company's distribution network.

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Efficacy vs. Risk: A Contemporary Review of Sunscreen Filters

Being protected from sunlight would seem essential to preventing DNA damage that leads to skin cancers; however, the sunscreen filters used pose some risks of their own. This brief review highlights the safety vs. risk of sunscreen filters and approaches to improving their efficacy.

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