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220 Results
Section: Testing > Safety/Stability
Testing
ECHA Speeds Regulatory Action for Hazardous Chemicals
To speed up identifying and managing the risks of hazardous chemicals, ECHA is screening structurally similar substances in groups. Last year, the agency, together with national authorities, reviewed around 220 high-volume substances, of which 56% required more hazard data.
Literature/Data
ZnO Nanoparticles Penetrate but Only Under These Conditions
Zinc oxide (ZnO) nanoparticles are a major component in sunscreens but their ability to permeate skin has remained undetermined. Recent work in
Applied Biomaterials
identifies the conditions under which they penetrate—notably, not in their nano form as they exist in sunscreens.
Methods/Tools
Do Nanomaterials Penetrate Skin? EUON Commissions Review Study
The EUON commissioned a literature review to explore the potential dermal absorption of nanomaterials. Results found the materials rarely penetrate intact skin, except for ionic silver, but a more standardized approach to testing is needed.
Animal Alternatives
GARDskin Provides Animal-free Way to Guard Skin
SenzaGen and XCellR8 have recently expanded its collaboration to offer GARDskin Animal Product-free, an animal-free skin sensitization assay safety assessment for chemicals in products.
Safety/Stability
Standardizing Safety: ISO Validation and Sun Protection Tests
In addition, methods under review pertaining to sun protection are discussed. The ISO sets proposed standards and test methods for nearly every industry; its validation process is described here.
Colorant
SCCS Concludes DHA is Safe for Hair Dyes
The SCCS released its opinion on dihydroxyacetone (DHA; 1,3-dihydroxy-2-propanone) at a plenary meeting held on March 4, 2020: the ingredient is safe for use as a hair coloring ingredient in leave-on treatments, and in self-tanning lotions and face creams.
Regional
FDA Issues Draft Guidance for Topical Drugs
Contact dermatitis from topical drugs and human safety are the topics in a recently issued guidance document made available by the FDA. Comments are sought through May 8, 2020.
Efficacy
With Skin Sensitivity Up, SGS Has Tolerance Testing Down
In a market where skin sensitivity claims continue to rise, SGS proposes methods here to determine product safety for skin; one of which is a skin tolerance test, to which successful products are awarded an official "seal."
Oral Care
What’s Your Environmental Impact?
Eurofins encourages consumers and formulators alike to monitor the environmental impact of cosmetic products. One way to achieve this is through an ecotoxicological test, which can pave the way for "green" products.
Animal Alternatives
Strat-M® Membrane for Transdermal Diffusion Testing – FREE Sample
Strat-M® membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin and is an alternative to animal testing. Learn more about this innovative technology and request a free sample.
News
DevaCurl Slapped with Class-action Lawsuit
The Manhattan Federal court suit states various DevaCurl products have caused "scalp irritation, excessive shedding, hair loss, thinning, breakage and/or balding during normal use."
Safety/Stability
Patch Testing, Irritation and Sensitization: Safety Testing in Cosmetics
An online exclusive by Anjali Salvi, Ph.D. about product safety and what needs to be done for consumers. Salvi discusses how regional conditions, intended use of the product and method of application can be a huge factor in determining product safety for consumers worldwide.
Regional
Greenbrier International/Dollar Tree Flagged for Acne Pad Import Violations
FDA inspections revealed violations at multiple foreign manufacturers that supply acne pads and drugs to the company's distribution network.
Literature/Data
Efficacy vs. Risk: A Contemporary Review of Sunscreen Filters
Being protected from sunlight would seem essential to preventing DNA damage that leads to skin cancers; however, the sunscreen filters used pose some risks of their own. This brief review highlights the safety vs. risk of sunscreen filters and approaches to improving their efficacy.
Anti-aging/Face
Anti-aging Safely: Bakuchiol for Skin-building Benefits
"Bakuchiol being non-irritating, as opposed to retinoic acid (which can cause irritation), is really the differentiating factor and what’s cause for excitement with this study."
Consumers/Market
Expert Opinions: Clean Beauty
Featuring insights on label transparency, performance, safety, greener chemistries, Pickering emulsions and more, this month's collection of "Expert Opinions" is all about clean beauty. Click through to the digital magazine for the complete article.
Safety/Stability
A Safety, Toxicity and Irritation Testing Primer
To ensure a product’s success, especially in light of ‘clean beauty’ tenets, it must be tested for stability as well as safety and efficacy. The following primer offers an overview of key tests to perform as products are developed and prepared for launch. Click through to the digital magazine for more.
Regional
FDA Alert: New J&J Baby Powder Recall
According to the FDA, a test sample from one lot was found to contain chrysotile fibers, a type of asbestos. As such, Oct. 18, 2019, Johnson & Johnson voluntarily recalled the product.
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