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18 Results
Type: Article
Section: Testing > Microbiology
Microbiology
Microbiological Considerations for Refillable Bulk Cosmetics: Survey and Commentary
The commercial sale of refillable products in bulk now includes liquid galenic formulas. Their diverse flow chains pose unique microbial challenges, as shown here, underlining the importance of flow chain planning and assessment tools/strategies.
Testing
Proposed Method to Evaluate the Microbiological Stability of Cosmetics During Use
The authors propose an approach to assess the microbial stability of a product during use, referred to as the Microbiological Use Test (MUT), and apply this analysis in case studies to predict the microbiological risk of commercial products. The described test has been used successfully in the development of cosmetics.
Literature/Data
Industry Insight: Microbiome Interactions and Skin Health
New research from Amway and Microbiome Insights underlines the connections between skin health and the microbiome. In our exclusive two-part podcast series, Greg Hillebrand, Ph.D., and Malcolm Kendall share what they've learned; following is an excerpt.
Efficacy
Industry Insight: Testing the Most Efficient Color Shampoo/Conditioner Duos
In this "Industry Insight," Sabina Wizemann, senior chemist of the Health, Beauty and Environmental Sciences Lab at the Good Housekeeping Institute has evaluated shampoo and conditioner pairs to identify the best performers for hair dye retention. In a recent interview, she explained how she tests these products, analyzes their efficacy and claims, and which duos exemplified the highest efficacy, compared with other products.
Testing
Fighting AGEs Formation: Upcycled Artichoke Inhibits Glycation, Increases Skin Firmness
Upcycling organic waste into cosmetics has been of interest for the growing sustainability trend—and artichoke, in particular, demonstrates anti-aging activities. Described herein is the development of an upcycled artichoke byproduct, which was tested for effects on skin glycation and elasticity.
Testing
Testing Tactics in Skin: Antiviral Response
In connection, with age, the skin’s immune system declines; i.e., immunosenescence. This largely unexplored area holds treatment and product development potential. COVID-19 is suspected of infecting the integumentary system and current literature reports related signs of cutaneous lesions.
Testing
Soothing Moves:
Cannabis Sativa
Cell Culture Alleviates Inflammation
The field cultivation of hemp is tasked by today’s large-scale demand. Here, a
Cannabis sativa
cell culture extract is proposed as a sustainable alternative. After initial characterization, the extract was tested as described here for efficacy against inflammatory markers for skin-soothing activities.
Consumers/Market
Opportunity in Diversity: Formulating for the Multiethnic Market
The expanding multicultural beauty market provides opportunity to formulate products specifically to the needs of ethnic skin types. Pigmentation is not the only difference between black and Caucasian skin, the skin barrier and other factors come into play.
Sensory
Testing Tactics in Skin: Keratinocytes as Sensory Nociceptors
Humans value senses of touch and warmth while enjoying their surroundings but pain and itch are also part of this experience. The present column explores Transient Receptor Proteins (TRPs), how they sense pain and itch, and their potential application in skin care and anti-aging products.
Safety/Stability
Free Formaldehyde Preservative Stability in Personal Care: Part II—Formulations
As scrutiny of formaldehyde-donor (FD) and other preservative technologies has increased in recent years, additional assurances of the relative safety and benefits of FD technologies are required. This two-part article examines the effects of temperature and pH on free-formaldehyde levels (as detected by C-13 NMR), first in water, then in personal care formulations.
Magazine
Stress and Psoriasis: How TCM Herbs Can 'Cool' Inflamed Skin
This study explores how TCM can be leveraged in skin products to holistically improve conditions such as psoriasis. In particular, properties of honeysuckle,
Rehmannia glutinosa
and rhubarb are described and tested here in vivo.
Safety/Stability
Free Formaldehyde Preservative Stability in Personal Care: Part I—Water
As scrutiny of formaldehyde-donor (FD) and other preservative technologies has increased in recent years, additional assurances of the relative safety and benefits of FD technologies are required. This two-part article examines the effects of temperature and pH on free-formaldehyde levels (as detected by C-13 NMR), first in water, then in personal care formulations.
Literature/Data
Givaudan Active Beauty Leads the Way in Skin Microbiome Research
At Givaudan, innovation is in our DNA: we thrive on the challenge of constantly pushing boundaries to develop new ideas and enhance existing concepts. In a bid to take our Active Beauty cosmetic ingredients to the next level, seven years ago we launched a pioneering research project into the relationship between the human microbiome and our health, beauty and well-being. Discover our dedicated video and be conquered.
Methods/Tools
Natural vs. Synthetic Antimicrobials and HDAC as an Indicator of Microflora Health
This article reviews the role of skin microflora in protecting skin, and assesses how the histone deacetylase (HDAC) enzyme is implicated. From this, HDAC expression is used as an indicator to compare the effects of traditional biocides and preservatives with natural antimicrobials on skin’s microbiome. Results suggest the latter effectively preserve products while maintaining a healthy microbiome.
Microbiology
Determining Preservative Efficacy in W/O Formulas, Part II: Making Microbiological Safety Assessments
The relevance of microbiological tests for w/o formulas has been questioned, mandating a more holistic approach. This second article in a series examines the failure rate of PETs for w/o products but looks at why this does not mean insufficient stability.
Testing
Mitigating 'Maskne:' Boldo to Balance Sebum, Bacteria and Redness in Acneic Skin
Peumus boldus
(boldo) extract was tested for effects on sebum production,
S. aureus
growth and
C. acnes
lipase activity in vitro, as well as on skin redness in vivo. This work aimed to develop a natural ingredient to control sebum, inhibit microbes and their activity, and reduce redness in acne-αfflicted skin.
Microbiology
Determining Preservative Efficacy in W/O Formulas, Part I: Test Performance and Limitations
Microbiological test methods for w/o formulas have raised questions in terms of suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods.
Tech/Equipment/Services
Assessing the Effects of Blue Light on the Skin in New Validated Method
Studies have shown blue light can have damaging effects on the skin. Genemarkers has developed a reproducible in vitro method for measuring blue light effects. Learn how Genemarkers’ blue light testing can aid product development.
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