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18 Results
Section: Research > Methods/Tools
Tech Transfer
Neural Networks Predict Material Structures, Behaviors Faster
A recent interview on Phys.org with Argonne National Laboratory Engineer Mark Messner explores how neural networks in AI could be used to predict material structures, given preferred properties, some 2,000+ times faster than standard simulations.
Efficacy
'Mirror, Mirror, in the Internet of Things. . .
...use great caution with the advice you bring.' Just what we need. Another critic scrutinizing appearance. And before coffee no less. Yet, this unbiased, digitized evaluation offers interesting potential; and if we don't like it, we can always turn it off.
Methods/Tools
Rubbing Shoulders with Massage for Improved Penetration
Rubbing is a common application method for topical products, though evidence of its efficacy remains scarce. The present article reviews research in support of this application theory. It also identifies what investigation is still needed.
Methods/Tools
Properties of Emulsions: Structure and Skin Penetration
This work studied the influence of emulsion type and structure on the penetration of vitamins as cosmetic active ingredients. An emulsion of the w/o type and two different o/w emulsions were compared with an oil solution as a standard. A systematic in vitro study of penetration into the stratum corneum and the living skin was performed with the isolated perfused bovide udder skin model. The results substantiate the influence of emulsion type and stucture on the degree of penetration of water-soluble and oil-soluble vitamins into the skin.
Actives
Don’t Count On Genetics, Sunscreens are the Best Bet
In a podcast with P&G scientists Frauke Neuser, Ph.D. and Rosemarie Osborne, Ph.D.,
Cosmetics & Toiletries
learned about genetic studies in support of the Olay brand, and more. Following is an excerpt.
Methods/Tools
Validating the Effectiveness of Rubbing on Percutaneous Penetration
The effect of rubbing on percutaneous penetration has long been questioned. Existing data regarding rubbing effects is sparse, and what is available is controversial at best. While some evidence suggests that rubbing increases absorption, others note the opposite. Further understanding of the rubbing effect on percutaneous penetration may offer a more complete picture in relation to the application of drugs, cosmetics and skin care.
Methods/Tools
Rapid Electrokinetic Patterning for Biological Analysis, Nanoassembly
Researchers at Purdue University have developed a rapid electrokinetic patterning technique using a laser and holograms to quickly position tiny particles for biological analyses or to create devices using nanoassembly.
Cosmetic Ingredients
Words from Wiechers: Without Penetration, No Delivery
This somewhat tongue-in-cheek edition of our "Words from Wiechers" series offers insight to improve the efficacy of actives.
Methods/Tools
Indena Genetically Validates Bilberry Extract
Indena has genetically confirmed the content of its bilberry extract, assuring the material's traceability and authenticity.
Literature/Data
Genetic Mutations Open Doors to Atopic Dermatitis
Atopic dermatitis may be caused by a single-gene mutation, according to new research published in
Nature Genetics
. Scientists believe the effects of the mutation could be partially corrected through glutamine supplementation.
Anti-aging/Face
[podcast] P&G Scientists on Personal Genetics and 'Good Agers'
P&G has been busy unraveling genetic mysteries to apply in new product concepts. How? This exclusive interview, with Olay scientists, explains. Listen now!
Literature/Data
Taking Shape: Genetic Facial Markers Discovered
Using novel 3D technology, researchers discovered 15 new genes that determine facial features, as published in
Nature Genetics
.
Methods/Tools
[podcast] Author Commentary: Epigenetics in Cosmetics, with Paul Lawrence, Ph.D.
Today,
Cosmetics & Toiletries
has a special treat for you. Paul Lawrence, Ph.D., co-author on a new three-part article series, shares insights on the potential for epigenetics in cosmetics—not coincidentally, the topic of the series. Listen now!
Methods/Tools
Do Nanomaterials Penetrate Skin? EUON Commissions Review Study
The EUON commissioned a literature review to explore the potential dermal absorption of nanomaterials. Results found the materials rarely penetrate intact skin, except for ionic silver, but a more standardized approach to testing is needed.
Actives
Elicitation of Rice Tissue Culture to Maximize Skin Epigenetic Modulation
Meristem cells of Himalayan red rice were cultured and elicited to produce secondary metabolites. Through an in vitro assay, rejuvenation was shown at the epigenetic level of treated cells. An increased expression of dermatopontin in keratinocytes, besides being a novel finding, implies that ReGeniStem™ Red Rice may be able to firm the skin and improve the skin barrier function.
Actives
Elicitation of Rice Tissue Culture to Maximize Skin Epigenetic Modulation
Meristem cells of Himalayan red rice were cultured and elicited to produce secondary metabolites. Through an in vitro assay, rejuvenation was shown at the epigenetic level of treated cells. An increased expression of dermatopontin in keratinocytes, besides being a novel finding, implies that ReGeniStem™ Red Rice may be able to firm the skin and improve the skin barrier function.
Method/Process
Moisturizer Penetration in Skin Revealed via Low-coherence Inferometry
Research published in the Russian journal
Engineering
describes a method to measure the penetration of gel moisturizers in skin in vivo via low-coherence interferometry.
SPF/Sun
[podcast] Sunscreen Innovation Act Update: MUsT Test and Penetration Potential
"What’s changed with respect to sunscreen evaluation is ... the test model they are using now is designed for drugs ...and has never been applied previously for the sunscreens," Epstein reports.
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