ct

Current cover

Recent in Testing (page 9 of 32)

Shrinking Pores at Their Core: Gallic Acid Derivate Controls ROS and Sebum Factors

Shrinking Pores at Their Core: Gallic Acid Derivate Controls ROS and Sebum Factors

Nov 16, 2017 | H. Chajra, A. Scandolera, M. Meunier and M. De Tollen, Givaudan Active Beauty, Toulouse and Pomacle, France

This study proposes a unique molecule derived from gallic acid to prevent enlarged and clogged facial pores. The ingredient is partly activated by the microbiome and protects against oxidative stress and excess sebum—two key factors at the core of enlarged pores.

New In Vitro Data for Alban Mullers Protectami Skin Defense Solution

New In Vitro Data for Alban Muller's Protectami Skin Defense Solution

Nov 8, 2017

The ingredient was found to increase skin elasticity by activating the synthesis and maturation of elastin, while decreasing the activity of elastase enzymatic degradation. It also increased cytokeratins and desmosomial proteins, and improved cell communication between keratinocytes.

BASF-Poietis Deal to Take 3D Bioprinting to Cellular Depths

BASF-Poietis Deal to Take 3D Bioprinting to Cellular Depths

Oct 31, 2017

BASF and 3D bioprinting expert Poietis have big plans to advance skin care. In an extended agreement, the two will collaborate to optimize the 3D bioprinting of skin equivalent models to study the effectiveness of actives.

Creme RIFM Model Reveals Aggregate Fragrance Exposure

Creme RIFM Model Reveals Aggregate Fragrance Exposure

Oct 22, 2017

Good news on the testing front: a model jointly developed by the Research Institute for Fragrance Materials and Creme Global recently showed consumer exposure to fragrances from personal care products tends to be over-estimated.

Are Your Sunscreens Infra-ready? New In vitro Method Puts Data Behind the Claims

Are Your Sunscreens Infra-ready? New In vitro Method Puts Data Behind the Claims

Sep 29, 2017 | Elise Delamour, Sébastien Miksa and Dominique Lutz, HelioScreen Labs, Creil, France

Considering more and more sun care products are claiming infrared (IR) protection, it is important to standardize the parameters by which they are evaluated. Since IR-A and IR-B are the most implicated in skin damage, a test method was developed based on these wavelengths, as described here.

Silab’s Whitonyl Witnesses New Data

Silab’s Whitonyl Witnesses New Data

Sep 18, 2017

Silab’s active helps control melanogenesis and its environment, and the company has come up with new data to prove the ingredient's efficacy. This ingredient can be utilized to enhance complexion radiance, with depigmenting and lightening action.

Recycled Skin: A U.S.-bound, Animal-alternative Test Substrate

Recycled Skin: A U.S.-bound, Animal-alternative Test Substrate

Sep 4, 2017

Unlike animal, bioprinted or lab-grown skin, real, live human skin that is viably maintained can more realistically provide data on the toxicity and efficacy of drugs and compounds of interest. This is the focus of U.S. biotech newcomer Genoskin.

New Ideas on Hair Breakage: Mending Existing Flaws

New Ideas on Hair Breakage: Mending Existing Flaws

Sep 3, 2017 | Trefor A. Evans, Ph.D., TRI-Princeton Princeton, New Jersey

Our historical beliefs as to the causes of hair breakage have been largely shaped by findings from testing approaches. More recently, an alternate mechanical testing technique, fatigue testing, has been changing our perspective on this topic.

Antidote for Aging: Synthetic Viper Venom Smooths Over a Cross-cultural Concern

Antidote for Aging: Synthetic Viper Venom Smooths Over a Cross-cultural Concern

Sep 2, 2017 | Remo Campiche, Marc Heidl, Rainer Voegeli and Dominik Imfeld, DSM Nutritional Products, Kaiseraugst, Switzerland; Pierre Séroul, Newtone Technologies, Lyon, France; and Anthony V. Rawlings, AVR Consulting Ltd., Northwich, England

DABBA is a synthetic peptide that mimics Waglerin-1, a toxin from the temple viper. It is shown here to reversibly inhibit muscular contraction and reduce wrinkle formation, and to induce the expression of genes that improve collagen fiber maturation. Notably, differences in anti-wrinkle effects were observed in different ethnicities.

Tox Testing at the Speed of Light (Really)

Tox Testing at the Speed of Light (Really)

Aug 22, 2017

Until now, testing chemicals for their toxicity has relied on reporter genes, which can take 24 hr to deliver results. A new approach from North Carolina State University, however, uses a modified protein that emits light when binding occurs—effectively signaling its safety.

Can't find what you're looking for? Try searching, or looking through past issues.