Search Cosmetics & Toiletries: Page 9

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Section: Testing > Method/Process

Biomimetic vs. Traditional Skin Moisturization: An In vivo Comparison*

To alleviate skin dryness, humectants and occlusive substances are traditionally used, mostly in combination. A third, relatively recent approach is biomimetic, i.e., active ingredients with lamellar structure containing skin-identical lipids. The aim of this study was to determine whether a biomimetic cream could deliver superior moisturization to human volunteers, compared with a conventional moisturizer containing petrolatum and mineral oil.

UV Transmission Assessment: Influence of Temperature on Substrate Surface

This work evaluates the impact of temperature on test substrate surfaces during the application, spreading and drying steps of the in vitro method to measure ultraviolet (UV) transmission. The authors work in a range between 20°C and 35°C, and demonstrate that controlling temperature is a key test parameter that should be strictly controlled to ensure reliability.

Tape Stripping Method in Humans: Comparison of Evaporimetric Methods

The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.

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In vitro/vivo SPF Correlation and Repeatability According to Substrate

This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.

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Massive Study Identifies Genetic Indicators for Skin Cancer Risk

The results of a massive study examining some 7,404 cases of squamous cell carcinoma in skin identified genetic associations with this disease, some for the first time.

*Depiction only; not an actual image from Kao Corp.

Kao Dually Visualizes Vessels, Capillaries in Deep Skin Tissue

An imaging technique based on an automatic visual extraction technology has been developed by Kao Corp to simultaneously collect capillary and blood vessel information. This will further skin care research.

In vivo Quantification of Corneocyte Lipids by Image Analysis

In a new method described here by the authors, fluorescence emitted from samples and captured by image analysis is used to quantify the number of lipids present in the cornified cell envelope. This in vivo approach is fast and noninvasive and could be used to screen molecules for potential moisturizing and restructuring effects.

Tape Stripping Method in Humans: Comparison of Evaporimetric Methods

The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.

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SPF Tests Reveal No Ideal In vitro Substrate Exists

In vitro SPF measurements are challenged by reproducibility, repeatability and correlation with in vivo values. Here, the authors assess sunscreen adhesion to the test substrate support, since poor adhesion produces bad results. Surface substrates are characterized by functional group, charge, wettability and surface morphology. Eight w/o and o/w emulsions also are tested. Results indicate an ideal in vitro test substrate does not exist.

Researcher Develops Probe for Non-invasive Below Skin Imaging

Jannick Rolland, PhD, an optics professor at the University of Rochester in New York, has developed an optical probe equipped with a liquid lens that takes images under the skin’s surface without the use of invasive procedures.

Influence of Pressure During Spreading on UV Transmission Results

This work evaluates the impact of applied pressure during sample spreading on the in vitro measurement of UV transmission. The authors work in a range of pressures between 50–200 g and demonstrate that pressure control is a key parameter that should be strictly controlled to ensure the reliability of test results.

CT1311 Miksa Eq 1

Influence of Pressure During Spreading on UV Transmission Results

This work evaluates the impact of applied pressure during sample spreading on the in vitro measurement of UV transmission. The authors work in a range of pressures between 50–200 g and demonstrate that pressure control is a key parameter that should be strictly controlled to ensure the reliability of test results.

In vitro/vivo SPF Correlation and Repeatability According to Substrate

This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.

UV Transmission Assessment: Influence of Temperature on Substrate Surface

This work evaluates the impact of temperature on test substrate surfaces during the application, spreading and drying steps of the in vitro method to measure ultraviolet (UV) transmission. The authors work in a range of temperatures, between 20°C to 35°C, and demonstrate that controlling temperature is a key parameter and should be strictly controlled to ensure reliability.

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Method to Reproduce In vitro Cosmetic Product Photostability Findings

The present article describes a reproducible method for determining the photostability of sunscreen products. This method is based in part on the in vitro determination of the UVA protection factor as proposed by Colipa for the irradiation aspect, and on the spectroscopy of a sunscreen in dilute solution for the absorbance measurement aspect.

Large-scale Screenings of Botanical Ingredients: Challenges and Opportunities

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

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Lake Makes a Splash in Redditch with New Lab

In support of customers who formulate and develop products in the cosmetics market, Lake Personal Care has opened a new laboratory to help progress production.

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Nagoya Protocol Takes Bio Products to 'Flask' in Korea

The Nagoya Protocol went into effect on August 17, 2017, in Korea. How might this impact the region, or even the greater cosmetics industry? It may be too soon to tell.

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