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Section: Testing > Method/Process

Researchers Mimic the Lymphatic System in Animal Alternative Chip

A chip created by L'Oréal and Hurel Corp. is designed to replace the local lymph node assay, a test often performed on cosmetic raw materials. In addition to saving animals, the chip is also said to be less expensive than animal testing. Hurel developed the working microfluidic portion of the chip.

Measuring Reactive Oxygen Species in Skin with Fluorescence Microscopy

Several signs of skin aging have been attributed to the presence of free radicals. This paper discusses the application of two-photon fluorescence microscopy to determine the effects of sample formulations on the number of reactive oxygen species (ROS) formed in skin models.

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Ceramides in Skin Stress: Ultraviolet, Tape Stripping, and Crowding

Stress induces changes in the ceramide content of the skin, and may lead to compromised barrier function or skin diseases. Skin has ways of responding to these stresses, as we review here in the case of skin stressed by tape stripping, organic solvents, overcrowding, and ultraviolet (UV) irradiation.

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IID Brings Front-end Innovation to 'Derm-termined' Product Developers

The International Investigative Dermatology meeting is more than meets the eye—or skin. It's about future targets for innovative OTC/topical products. Just ask Rodan + Fields, Mary Kay, Estée Lauder and others.

C + K Devices Used in Space to Quantify Skin Aging

Skin measurement devices from Courage + Khazaka Devices have been used for the second time on the International Space Station (ISS) to verify skin aging in space

In Vitro Methods to Test Materials for Ozone Protective Capabilities

Many markers can be used to indicate epidermal stress. Therefore, it becomes clear that the skin is also a sensitive target to ozone exposure and one that could greatly benefit from cosmetic or personal care materials designed to protect against ozone.

Video Imaging in the Measurement of Makeup Efficacy and Performance

Video imaging techniques add quantitative data about the visual effects of makeup when evaluating efficacy and performance of products such as mascaras, lip colorants, facial foundations and nail enamels.

Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!

Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.

Detecting Estrogenic Endocrine Disruptors in Personal Care Products and Supplements

Endocrine disruptor chemicals (EDCs) are a class of chemicals that has raised alarm for being linked to a wide variety of detrimental effects on human and wildlife populations, e.g., cancers, precocious puberty and obesity. Thus, there is a need to test personal care products and supplements for EDCs, which can be accomplished using the validated bioassay described here.

Patent Pick: Approach to Screen Actives on ECM In situ

Patent Picks are chosen by the editors from publicly available sources. Today's feature describes an immunological technique to screen for the effects of new cosmetic or pharma actives on ECM molecules in situ.

Shaving And Its Effects On Percutaneous Absorption In The Skin

Shaving and its Effects on Percutaneous Absorption in the Skin*

Despite its being an area of concern for many years, the percutaneous absorption of cosmetics has not been rigorously studied. Additionally, the effects of shaving on this process are relatively unknown. An overview of recent research reveals that more research in this area is required.

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The ‘Skin’ Crowd: Emerging Trends for Technology in Skin Care

As skin care becomes more scientific, consumers are making it a point to better understand their products. Apps and brands tailoring to the consumer experience are amassing a growing following, leading to shifts in purchasing dynamics.

The salon will provide in-house product evaluations that will assist in developing products with relevance and consumer acceptance in the sub-Saharan African market.

BASF Opens Skin and Hair Care Evaluation Salon in Nigeria

The salon will provide in-house evaluations to assist in developing products with relevance to and consumer acceptance in the sub-Saharan African market.

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One Ingredient, Twice the Benefits for Pores and Age Spots

DSM has created a solution to benefit two skin problems at once. The company’s latest skin care ingredient helps eliminate facial pores and age spots simultaneously. Additionally, helps the skin look younger and improves appearance after the age of 30.

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C + K Introduces Tewameter with Three Probes for Better Efficiency

Courage + Khazaka has upgraded its well-known TEWL and barrier function measurement device, the Tewameter, with three probe heads for better efficiency.

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Comparatively Speaking: The INCI Names vs. Properties of Silicone Surfactants

Surface tension is a ruling factor in the formulator's world. In this edition of "Comparatively Speaking," Tony O'Lenick explains its influence on foam and wetting; he also demonstrates how little the INCI name reveals about a material's properties.

Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!

Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.

Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing

Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.

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