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Section: Testing > Method/Process

In Vitro Methods to Test Materials for Ozone Protective Capabilities

Many markers can be used to indicate epidermal stress. Therefore, it becomes clear that the skin is also a sensitive target to ozone exposure and one that could greatly benefit from cosmetic or personal care materials designed to protect against ozone.

Hair Color Vibrance Factor to Characterize Shine and Color Intensity*

To evaluate the comprehensive effects of shine and color intensity in hair, a hair color vibrance factor has been developed to enable new claims for hair dye formulas and after-dye treatments. Experimental results described here show how varying the ingredients in shine spray and hair dye formulas affect this factor and correlate with subjective panelist assessments.

Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing

Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.

Evaluating Droplet Size in Nanoemulsions from a Novel Emulsifier System

This article describes two sophisticated techniques to measure the diameter of emulsion droplets on the nanometer scale and uses those techniques to test a new emulsifying agent capable of spontaneously creating emulsions with droplet sizes smaller than 300 nm.

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Testing Tactics in Skin: A View of Visible Light Protection

Blue light, in particular, may be responsible for most of the adverse skin reactions caused by visible wavelengths. This column reviews methods to screen for materials that protect against blue light but also allow its benefits to shine through.

Detecting Estrogenic Endocrine Disruptors in Personal Care Products and Supplements

Endocrine disruptor chemicals (EDCs) are a class of chemicals that has raised alarm for being linked to a wide variety of detrimental effects on human and wildlife populations, e.g., cancers, precocious puberty and obesity. Thus, there is a need to test personal care products and supplements for EDCs, which can be accomplished using the validated bioassay described here.

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Planting Ideas: Upcycled Rubber Seed Offers a Renewable Cosmetic Ingredient

The sustainable utilization of by-products from the para rubber production industry is presented here for cosmetics. Experiments confirmed the safety of para rubber seed oil, in addition to antioxidant and skin-lightening efficacies.

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Kunming Institute Brands Dendrobium with Dr. Plant, Uncovers Milkweed's Potential

Researchers at The Kunming Institute of Botany in China have uncovered natural compounds with real skin care potential. While Dr. Plant teamed up to bring dendrobium to market, new findings in milkweed present brands new opportunities.

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Sandblasting to Improve the Reproducibility of In vitro Sunscreen Evaluation

SPF test results from substrates treated using a traditional sandblasting technique are compared with those from substrates treated using a new process. Based on the topographic control of 10 batches and 34 sunscreen evaluations, the authors concluded the new process had better topographic reproducibility, consequently improving the SPF repeatability and reproducibility in vitro.

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'Behind the Gloss'—Multiple Angles Reveal New Soft-focus Insights

Described here is a novel method to investigate the soft-focus effects of powders. It utilizes a handheld, multi-angle spectrophotometer to capture reflectance spectra at various observation angles. Results showed variances in results taken in the trans or “behind the gloss” plane, indicating which powders provide the best light-scattering capabilities.

Antiaging in a Different Light: Assessing How Chromophores Color Perception

Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.

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Beauty Accelerate Virtual: Inclusive Design Means Better Beauty for All

Designing products to meet the unique needs of disabled consumers can translate to better product experiences for all. Hear more about this during our panel discussion at Beauty Accelerate Virtual—to be held Oct. 18-21, 2021.

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VIDEO: P&G Scientists on Claims Substantiation in Anti-dandruff Care

Head & Shoulders recruits an army to prove the benefits its brand delivers to consumers. Hear more in this video.

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VIDEO: Lesson Learned: Consumer Sensibilities are Crucial in R&D – Gallagher

In a recent exclusive interview with C&T, Kevin Gallagher, Croda’s retiring president of personal care/actives, revealed how being sensitive to consumer concerns extends beyond the marketing of products all the way into the lab. See what he talked about with C&T’s Rachel Grabenhofer.

Antiaging in a Different Light: Assessing How Chromophores Color Perception

Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.

Liquid Crystals in O/W Emulsions with Urea: Development and Testing

Using a ternary phase diagram, the authors developed systems based on nonionic surfactants, light paraffin oil, water, and (optionally) urea. Systems in which lamellar liquid crystals formed and in which urea was an ingredient showed higher occlusive power and lower TEWL in in vitro tests.

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Countering P. acnes: In vitro Approaches to Anti-acne Testing

Acne is thought to be caused by the Propionibacterium acnes (P. acnes) bacteria, with widespread effects. The assays described in this article may provide a starting point with which to screen novel materials to treat the condition.

High-throughput screening, AI and modeling, and other digital tools are ramping up the pace of new cosmetic ingredient technology discovery and product development. Learn more at Beauty Accelerate 2022.

Beauty Accelerate 2022: Tech x Beauty to Accelerate R&D Innovation

The session will inspire attendees by considering the ways emerging technologies can make innovation more efficient while rendering brands nimble enough to respond to shifting consumer and supply chain realities.

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