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Section: Cosmetic Ingredients > Actives
Literature/Data
Patent Pick: Conjugated, Penetrating Botulinum Toxin
Patent Picks are chosen by the editors from publicly available sources. Today's patent relates to a cell-penetrating peptide fused to a botulinum toxin recombinant protein, for cosmetic and other purposes.
Actives
Native Extracts x Nutrafruit Reveal ‘Royal’ Natural Active: Queen Garnet
Native Extracts and Nutrafruit have partnered to deliver a topical extract and nutricosmetic that are Japanese plum-based.
Literature/Data
Study Uncovers Genetic Predispositions to Skin Cancer
Basal cell carcinoma is the most common cancer worldwide, with an annual incidence of 2.8 million cases in the United States alone. A recent study found 31 genetic markers for the disease, 14 of which were identified for the first time.
Literature/Data
ZnO Nanoparticles Penetrate but Only Under These Conditions
Zinc oxide (ZnO) nanoparticles are a major component in sunscreens but their ability to permeate skin has remained undetermined. Recent work in
Applied Biomaterials
identifies the conditions under which they penetrate—notably, not in their nano form as they exist in sunscreens.
Anti-aging/Face
Givaudan Chronoglow Combines AI and Epigenetics for Skin Radiance
Givaudan Active Beauty unveils Chronoglow, combining AI and biomimetic epigenetics to improve skin elasticity, luminosity and radiance.
Methods/Tools
[podcast] Author Commentary: Epigenetics in Cosmetics, with Paul Lawrence, Ph.D.
Today,
Cosmetics & Toiletries
has a special treat for you. Paul Lawrence, Ph.D., co-author on a new three-part article series, shares insights on the potential for epigenetics in cosmetics—not coincidentally, the topic of the series. Listen now!
Event Coverage
SCC Tackles Claims Substantiation and Genetic Testing at Annual Meeting
At the Society of Cosmetic Chemists' (SCC) Annual Scientific Meeting and Technology Showcase, which took place on Dec. 12-13, 2013 at the New York Hilton, pertinent subjects were tackled, such as modern claims substantiation, nanomaterials, genetic testing and cosmetic dermatology.
Literature/Data
K18 Granted Patent for Hair Fiber-penetrating Peptides
San Francisco-based indie brand K18 has been awarded a patent for peptides that can penetrate the hair fiber to improve its strength and hydrophobicity, and that have more affinity to hair keratin than previously developed peptides.
Actives
Cosmetic Victories Finalist Profile: Penetrating Peptide for Enhanced ROS Elimination
Human eosinophil cationic protein was utilized as a carrier in this invention from ImDerma Laboratories to quickly penetrate skin cells and deliver high antioxidant efficacy with a low dose of EGCG.
Literature/Data
Over the Top: Histone Deacetylase Inhibitors for Restorative Epigenetic Skin Care
The skin care industry has begun to explore epigenetics to ameliorate skin conditions. Within this field, histone deacetylase inhibitors (HDACis) are of interest thanks to their potent anti-inflammatory and other anti-aging effects. This article reviews their activity and utility.
Skin Care
Build the Basics, Optimize Products, Formulate Naturals and Penetrate Skin
In addition to courses for the beginning chemist, natural products and optimization of formulas,
Cosmetics & Toiletries
has added
Physiology of the Skin
, featuring Zoe Diana Draelos, MD, to its online training program. Buy at Suppliers' Day and save! Visit booth 1345.
Actives
Elicitation of Rice Tissue Culture to Maximize Skin Epigenetic Modulation
Meristem cells of Himalayan red rice were cultured and elicited to produce secondary metabolites. Through an in vitro assay, rejuvenation was shown at the epigenetic level of treated cells. An increased expression of dermatopontin in keratinocytes, besides being a novel finding, implies that ReGeniStem™ Red Rice may be able to firm the skin and improve the skin barrier function.
Actives
Epi-On™– Holistic skin recovery through epigenetic pathway – efficacy study
A weakened skin barrier can be vulnerable and irritated to the environment. With the cold weather coming, our skin barrier needs a faster restorative and rejuvenating treatment.
Actives
Elicitation of Rice Tissue Culture to Maximize Skin Epigenetic Modulation
Meristem cells of Himalayan red rice were cultured and elicited to produce secondary metabolites. Through an in vitro assay, rejuvenation was shown at the epigenetic level of treated cells. An increased expression of dermatopontin in keratinocytes, besides being a novel finding, implies that ReGeniStem™ Red Rice may be able to firm the skin and improve the skin barrier function.
Actives
Garnet Continues to Develop Cell-based Therapy Platform for Skin Healing
The first in a series of cell products will be called GBT 009, and it will be capable of reducing inflammation and promoting healing.
SPF/Sun
[podcast] Sunscreen Innovation Act Update: MUsT Test and Penetration Potential
"What’s changed with respect to sunscreen evaluation is ... the test model they are using now is designed for drugs ...and has never been applied previously for the sunscreens," Epstein reports.
Literature/Data
Patent Picks— Electromagnetic Radiation, Omentum, Plant Extracts, Growth Factors, Gingerone and More
Chosen biweekly for their relevance to personal care, Patent Picks are taken from publicly available sources. This edition features patents related to active ingredients for skin benefits and to address hair loss.
Hair Care
Product Spotlight: Love Beauty and Planet Hyaluronic Acid Weightless Volume Vegan Shampoo
Technical advances have enabled hair products enriched with actives such as peptides, keratin, biotin and hyaluronic acid to promote hair strength, moisture retention and elasticity. Love Beauty and Planet's Hyaluronic Acid Shampoo offers a good example.
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