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Section: Testing

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FDA Sets Regulatory Framework for Regenerative Biological Therapies

It's a sign of the times when technology and innovation hit a point where the U.S. Food and Drug Administration must stop and write new rules to ensure consumer safety. That time, with respect to regenerative biological therapies, is now.

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Tox Testing at the Speed of Light (Really)

Until now, testing chemicals for their toxicity has relied on reporter genes, which can take 24 hr to deliver results. A new approach from North Carolina State University, however, uses a modified protein that emits light when binding occurs—effectively signaling its safety.

Raspberry Could Ride Anti-pollution to the Top

Raspberry is trending, not only for its impact on skin erythema and melanin, but for repair and antioxidant benefits. It's in the perfect position to ride the anti-pollution trend to the top.

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Opportunity in Diversity: Formulating for the Multiethnic Market

The expanding multicultural beauty market provides opportunity to formulate products specifically to the needs of ethnic skin types. Pigmentation is not the only difference between black and Caucasian skin, the skin barrier and other factors come into play.

A real challenge in the assessment of consumer emotional responses has been the need for validated but meaningful measures. Commentary outlined are benefits and drawbacks of various methods and asks the larger question of precisely what’s being measured.

The Emotion Paradox in Product Testing: A Commentary

A real challenge in the assessment of consumer emotional responses has been the need for validated but meaningful measures. Commentary outlined are benefits and drawbacks of various methods and asks the larger question of precisely what’s being measured.

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SPF Debate Puts Derms to the Test

Is the word we're spreading about sunscreen efficacy wrong? A new paper in the Journal of the American Medical Association thinks so. It holds that SPF values above 30 do make a difference.

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[podcast] The Sound and Scent of Efficacy

"While the consumer will think of ... feeling the softness of hair or smoothness of skin, our research has shown that none of our experiences is just unisensory. ...If we know that perception is multisensory, we start thinking about the role [of other senses]." Learn more from Charles Spence, Ph.D., in this seven-part podcast series, sponsored by Berjé.

Johann W. Wiechers, Ph.D.

Words from Wiechers: The Power of Suggestion

In this edition of our Words from Wiechers series, the late author explains the power of belief in product efficacy—and why products should be evaluated based on the perceived value they deliver to consumers.

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Nestlé Sets Out to 'Master the Microbiome'

Nestlé Health Science has entered the microbiome research sphere with the creation of Microbiome Diagnostic Partners, a joint venture with Enterome.

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Bee Venom is Back in the Buzz

Bee venom is back, this time with data. According to a thesis from the University of Strathclyde, previous reports of its effects were anecdotal and incomplete. Now there's science backing it; especially in terms of safety.

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Shiseido Tech Takes Personalization to the Exposome

How can custom skin care become more customized? Shiseido believes by plotting skin conditions in real-time as a function of environmental factors. A new smart phone-driven system does just that.

The Nagoya Protocol for Cosmetics and Extracts

The Nagoya Protocol is an international law applying to genetic resources and ensuring the countries of origin share in the benefits from using these materials.

Skin Toxicology—The Future May Be Orange

Here, industry expert Johann Wiechers, PhD, discusses the frequent use of percentages by toxicologists to calculate skin penetration. To relate this discussion to modern day events, Wiechers describes the skin penetration of orange paint, used by fans of the Dutch national football team.

Predicting the Percutaneous Penetration of Cosmetic Ingredients

While previous algorithms for predicting the skin absorption of permeants was based on in vitro data, the present article proposes a quantitative structure-activity relationship (QSAR) model based on in vivo human data. Here, a set of human in vivo data is described that provides entry into predicting the penetration of cosmetic ingredients.

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Tress Stress: How the Environment Affects Hair

The drive for "anti-pollution" personal care may not apply to hair care as strongly as other segments. Despite this, environmental stressors can impact hair's chemistry. This column provides a scientific basis by which formulation and claims strategies might be constructed.

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Managing Adversities: Atopic Dermatitis and the Microbiome

The AD process and S. aureus provide targets for intervention, which can be explored in vitro as described here. Although not causative, there is a strong correlation between the severity of AD and density of S. aureus in the microbiome.

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Skin Microbiome Manipulation as a Therapeutic Opportunity?

A review published in the Computational and Structural Biotechnology Journal explores the current state of the art in skin microbiome manipulation and transplantation for potential therapies.

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[podcast] The Bigger Issue Behind Microbial Contamination

Many cosmetic recalls in the U.S. relate to microbial contamination but not for the reason you might think. Here, experts from the Univ. of Cincinnati and PCPC explain why it's more than alternative preservatives to blame. Listen now. It's free.

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