Collagens I and III, and Elastin Activation for Anti-aging

Skin chronological aging, also called intrinsic aging, has been characterized on a microscopic level by reductions in total collagen content, elastin synthesis1 and hyaluronic acid content. These reductions are due, in part, to the cells involved becoming senescent and losing their synthesis capabilities.2 Decreases in these skin components further lead to decreased skin thickness, modifications of skin anisotropy, and the loss of skin firmness and elasticity, which are visible at the macroscopic level.

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