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Recent in Testing (page 28 of 34)

Noninvasive Techniques for Anti-cellulite Product Efficacy Evaluation

Noninvasive Techniques for Anti-cellulite Product Efficacy Evaluation

Jul 15, 2013 | K. Bazela, PhD; R. Debowska, PhD; B. Tyszczuk; K. Rogiewicz, PhD; and I. Eris, PhD, Dr. Irena Eris Cosmetic Laboratories; R. Mlosek, PhD, Medical University of Warsaw; and A. Nowicki, PhD, Institute of Fundamental Technological Research

Although cellulite is not considered a disease, it is a significant cosmetic problem for many post-adolescent women. Recent studies using new diagnostic techniques such as ultrasound imaging can define the cellulite-reducing efficacy of cosmetics. However, there is still a need to standardize and objectify the testing procedures and to find parameters to measure anti-cellulite efficacy.

In Sight—QOL Testing: Complementing Clinicals

Jul 12, 2013 | K. Schaefer, Cosmetics & Toiletries magazine

Personal care efficacy tests are known to test the physical effects or toxicity of products, often omitting more abstract and possibly equally as important factors such as well-being.

Ethics, Ethics Everywhere

Jul 12, 2013 | Katie Schaefer, Cosmetics & Toiletries magazine

Nowadays, however, personal care has evolved even further to encompass the root of human being-ethics and morals, where the purchase of a personal care item relates to one’s concern about the environment and animal welfare. But the involvement of ethics does not just apply to the consumers using the products; it applies to scientists conducting safety studies.

Responsilbilities in Outsourcing Clinical Testing

Jul 10, 2013 | Theresa Callaghan, PhD

It remains the responsibility of the manufacturer to substantiate the safety of both ingredients and finished cosmetic products prior to their being marketed.

The Air Up There: Skin VOCs

Jul 10, 2013 | Katie Schaefer, C&T magazine

In 2001, Japanese researchers reported that after the age of 40, some individuals develop a malodor known as “aging odor,” attributed to the presence of unsaturated C9, 2-nonenal. George Preti, PhD, a member of Monell Chemical Senses Center and an adjunct professor of dermatology at the University of Pennsylvania School of Medicine, was interested by this report and began to conduct research of his own.

UV Transmission Assessment: Influence of Temperature on Substrate Surface

Jul 1, 2013 | Sébastien Miksa, Dominique Lutz and Céline Guy, HelioScreen Labs

This work evaluates the impact of temperature on test substrate surfaces during the application, spreading and drying steps of the in vitro method to measure ultraviolet (UV) transmission. The authors work in a range between 20°C and 35°C, and demonstrate that controlling temperature is a key test parameter that should be strictly controlled to ensure reliability.

Determining Korean Consumers’ Degree of Exposure to Lipstick and Face Creams

Jun 25, 2013 | Kwangsuk Joo, Ongsoo Kim, Heonsik Kim and Jeungyeun Yoon, Hyechon College; and Jeongrim Ahn, Junkee Jang and Jaeun Song, Cosmetic Association

This study describes methods used in a Korean study to calculate consumer exposure to lipstick and face creams. The average amount applied daily was estimated and compared with data collected by weighing containers before and after use. The data collected was 1.8 to 1.6 times greater than the estimate, so although the survey represented real use patterns, the actual data was more accurate.

‘How Did THAT Get in There?’ Identifying Particulate Contamination in Products and Packaging

Jun 25, 2013 | Kathleen A. Martin, PhD, McCrone Associates Inc.

Particulate contamination and discoloration may occur in products due to foreign materials introduced via raw materials or during the manufacturing process. Agglomeration or reactions between ingredients and packaging components also are possible sources. The identification of contaminants and their origin, described here, is therefore critical so that future incidents can be prevented and safety or regulatory concerns can be addressed.

Evaluating Water Permeability and Occlusion in Wound Dressings and Topical Cosmetics

Jun 20, 2013 | Hongbo Zhai, MD, and Howard I. Maibach, MD, University of California

The present study uses an evaporimeter to measure the degree of water loss from in vitro skin samples covered by occlusive and semi-occlusive wound dressings to serve as a model for determining the effectiveness of occlusive cosmetic formulations. The purpose of this work was to develop a model for determining the effectiveness of occlusive cosmetic formulations.

DNA: Hard Evidence of Cosmeceutical Claims

Jun 19, 2013 | Katie Schaefer, Cosmetics & Toiletries magazine

To support finished product or raw material claims these two in vitro methods—the Affymetrix microarray and the Taqman Real Time Polymerase Chain Reaction (PCR)—measure the up-regulation or down-regulation of genes.

In Vitro Model for Decontamination of Human Skin

Jun 19, 2013 | Hongbo Zhai, MD, University of California; and Howard I. Maibach, MD, University of California School of Medicine

The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.

Fluid Skin Imaging for Better Resolution

Jun 14, 2013 | Katie Schaefer, Cosmetics & Toiletries magazine

Noninvasive subcutaneous skin imaging is a tool sought for use by the medical, pharmaceutical and personal care industries, but techniques have been lacking due to resolution and speed constraints.

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