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15 Results
Type: Article
Section: Testing > Microbiology
Anti-aging/Face
Safe and Strategic: Hyaluronic and Retinoic Acid Derivative Allays Aging and Acne
A hyaluronic acid and retinoic acid derivative were developed to combine their individual anti-acne and anti-aging efficacies. In vitro and in vivo testing, described here, showed the conjugate penetrated skin to exert the desired biological activities—in low concentrations and without irritation.
Literature/Data
Industry Insight: Microbiome Interactions and Skin Health
New research from Amway and Microbiome Insights underlines the connections between skin health and the microbiome. In our exclusive two-part podcast series, Greg Hillebrand, Ph.D., and Malcolm Kendall share what they've learned; following is an excerpt.
Testing
Q&A: How Do Conventional and Accelerated Preservative Tests Compare?
"How do accelerated and conventional preservative testing compare? What can each measure?" This reader inquiry led us to John Yablonski, of BioControl, who provided the following answer.
Microbiology
Microbiological Considerations for Refillable Bulk Cosmetics: Survey and Commentary
The commercial sale of refillable products in bulk now includes liquid galenic formulas. Their diverse flow chains pose unique microbial challenges, as shown here, underlining the importance of flow chain planning and assessment tools/strategies.
Microbiology
Niacinamide Platform Delivers Double Duty to Protect Products and Skin
Niacinamide is known for its skin benefits. Here, select ingredients were combined with it and explored for the potential to also protect against contamination. MIC data and challenge testing are presented, supporting the ingredient’s dual functionality.
Magazine
Stress and Psoriasis: How TCM Herbs Can 'Cool' Inflamed Skin
This study explores how TCM can be leveraged in skin products to holistically improve conditions such as psoriasis. In particular, properties of honeysuckle,
Rehmannia glutinosa
and rhubarb are described and tested here in vivo.
Skin Care
When Acne Attacks, Hexylresorcinol and Ethyl Linoleate Fight Back (part I)
Although
P. acnes
is a commensal bacterium of normal skin, together with the sebaceous gland, it clearly is implicated in acne. Here,
P. acnes
and other possible causes are reviewed, and a hexylresorcinol and ethyl linoleate anti-acne treatment to target them is described.
Tech/Equipment/Services
Is Your Microbiology Lab FDA-compliant? Part I: Personnel, Facilities and Equipment
This two-part article provides an overview of areas relevant to the U.S. Food and Drug Administration’s (FDA’s) inspection of cosmetic microbiology laboratories. Part II will appear in our July 2018 edition.
Testing
Propanediol Caprylate: Shifting the Microbiome, Sebum Levels and Classic Approach to Dandruff
Propanediol caprylate was previously shown to deactivate
Malassezia
for dandruff control. In parallel, its effects to shift the balance of
Cutibacterium
and
Staphylococcus
in the scalp microbiome, and reduce dandruff and sebum are explored here.
Skin Care
When Acne Attacks, Hexylresorcinol and Ethyl Linoleate Fight Back: Experimental (part II)
Although
P. acnes
is a commensal bacterium of normal skin, together with the sebaceous gland, it clearly is implicated in acne. Here,
P. acnes
and other possible causes are reviewed, and a hexylresorcinol and ethyl linoleate anti-acne treatment to target them is described.
Methods/Tools
Natural vs. Synthetic Antimicrobials and HDAC as an Indicator of Microflora Health
This article reviews the role of skin microflora in protecting skin, and assesses how the histone deacetylase (HDAC) enzyme is implicated. From this, HDAC expression is used as an indicator to compare the effects of traditional biocides and preservatives with natural antimicrobials on skin’s microbiome. Results suggest the latter effectively preserve products while maintaining a healthy microbiome.
Testing
Mitigating 'Maskne:' Boldo to Balance Sebum, Bacteria and Redness in Acneic Skin
Peumus boldus
(boldo) extract was tested for effects on sebum production,
S. aureus
growth and
C. acnes
lipase activity in vitro, as well as on skin redness in vivo. This work aimed to develop a natural ingredient to control sebum, inhibit microbes and their activity, and reduce redness in acne-αfflicted skin.
Literature/Data
Patent Picks—Microbe Separation, Emulsion Arrays and Salicylic Acid Delivery From Powder
Patent Picks are compiled by the editors from publicly available sources. This edition features processes for identifying microorganisms, forming emulsion arrays and delivering salicylic acid from powder.
Microbiology
Determining Preservative Efficacy in W/O Formulas, Part I: Test Performance and Limitations
Microbiological test methods for w/o formulas have raised questions in terms of suitability. They also require a more critical view of the results than other product types. This first article in a two-part series reviews the limitations of such methods.
Tech/Equipment/Services
Is Your Microbiology Lab FDA-compliant? Part II: Cultures, Growth Media, Reagents and Testing
This two-part article provides an overview of areas relevant to the U.S. Food and Drug Administration’s (FDA’s) inspection of cosmetic microbiology laboratories. Part 1 covered personnel, facilities and equipment, test materials and procedures, and documentation. Part 2 addresses microbial cultures and growth media, biochemical reagents, test procedures and more.
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