Search Cosmetics & Toiletries

71 Results

Type: Article

Section: Testing > Efficacy

PneumaNitricOxide850x425

Pneuma Nitric Oxide-generating Serum Shown to Improve Acne and Scarring

A pilot study published in the International Journal of Pharmaceutica Analytica Acta describes how a topical nitric oxide-generating serum reduced active pustules, comedones and scarring by reducing inflammation and keratinization in acne.

To prevent and repair UV-induced skin damage, a sustainable ingredient was developed from Sargassum vulgare, a brown seaweed that naturally evolved phlorotannins to defend against UV damage. The algae was fermented using a proprietary yeast to enrich this bioactive content; the resulting ingredient was tested as described here for skin benefits.

Brown Seaweed Ferment Propagates UV Damage Protection for Skin

To prevent and repair UV-induced skin damage, a sustainable ingredient was developed from Sargassum vulgare, a brown seaweed that naturally evolved phlorotannins to defend against UV damage.

TrendyEthnicWoman850x425

Total Breakdown: Recovering Anti-aging Efficacy After Collagen Fragmentation

When collagen breaks down, the broken fragments can hinder the performance of anti-aging actives over time. This column examines methods by which materials can overcome these aging-related issues in collagen production.

Chemists In Lab Studying Plant Samples In Test Tubes Adobe Stock 535785298

Bio + Chemo Guidance Uncover New Benefits in Known Naturals: Murraya Koenigii Extract Case Study

Murraya koenigii extracts derived via various techniques were compared. One developed through chem- and bio-guidance paired with a natural deep eutectic technology uncovered lesser-known efficacies, leading to a natural active to boost elastin synthesis.

RedheadedWomanSensitiveSkin850x425

Aubergine Mutes TRPV1 and Boosts TRPV-3 and -4 to Reinforce and Comfort Skin

While the causes of sensitive skin are not confirmed, they most likely are due to a neurogenic inflammation after the enhanced activation of sensory proteins in keratinocytes. The present work tested the ability of a Solanum melongena (aubergine) cell culture extract to inhibit sensory mediators of discomfort and activate barrier-boosting pathways.

Sourcing and Using Maca and Suma Roots

In recent years, interest in sourcing plant roots as active ingredients for cosmetic use has grown tremendously. Roots such as maca and suma are rich in secondary metabolites and, as described here, can have specific actions on skin to increase its vitality and response to environmental stresses.

Collagens I and III, and Elastin Activation for Anti-aging

As an alternative to semi-invasive facial rejuvenation techniques, the authors developed an active ingredient to reactivate senescent fibroblasts by stimulating metabolic pathways for collagens I and III, and elastin. The biological activity of the resulting ingredient is investigated here using in vitro models, ex vivo explants and human volunteers.

TwoWomenSelfieHealthyHair850x425

Dual Defense: Protecting and Repairing Hair Holistically, Inside and Out

Cumulative stress encountered by hair during daily grooming causes breakage and other forms of damage. This paper presents a holistic approach to protect hair from within and without by targeting the cortex and cuticle sheath. Fatigue testing and other assessments are carried out to determine efficacy.

CT2102_Suthiwa_850x425

Simple and Sensorial: Amino-modified Silicone Protects and Revives Hair

Multifunctional ingredients can simplify hair care routines by offering protection, performance and sensory benefits in one step. Herein, a terminal hydroxy amino-modified silicone is tested for its effects on hair breakage, drying time, wet and dry combing, colorfastness and more.

Longhairshrugging850

Restoring Hair and Scalp Health: Ceramide-2 Analog for Conditioning and Barrier Benefits

Since ceramides are essential for protecting skin and hair, the natural conclusion would be to use them as cosmetic ingredients. However, naturally occurring ceramides are difficult to extract and can carry a high cost. A structural analog to naturally occurring ceramide-2 was therefore developed.

Young Beautiful Multiracial Girl Smiling Using Facial Skin Care

Modeling and Targeting Cell Communication, Senescence and Immunoevasion to Support Skin Longevity

The present work sought to develop in vitro models to study the mechanisms of key hallmarks of aging: cellular communication, senescence and immunoevasion. The models were then used to test the efficacy of natural actives targeting these mechanisms.

CT1810_Gonzalez_pic1_850x425

Sticking it to Hair Damage: Delivery Duo Protects and Repairs Inside and Out

To adequately protect hair from damage, an efficient solution should offer not only high coverage externally, but also penetrate hair to impart reparative effects internally. The present study explores the ability of a dual technology to provide these benefits, as demonstrated via analytical techniques.

Pictured here is a clinical test subject before/after captured by Visia skin analysis. This image was created during a clinical test of RoC Skincare RoC 35 protocol users. All tests were conducted at clinics in France, with participants aged 45-plus, who reported their skin looked an average of 9.6 years younger after 90 days.

Beauty Before-and-Afters: How Better Imagery, AI, Social Media and Testing Are Changing the Game

“A high-quality before and after image offers a huge range of benefits. It pushes transparency. You’re no longer stating a claim, you’re demonstrating it."

The present study examined the effects of commercially available jojoba esters in liquid, natural jojoba-like form in three studies measuring irritation mitigation, skin hydration and soothing properties.

Jojoba Oil Esters Ease Inflammation, Sensitivity and Water Loss from Skin and the Environment

Water scarcity has become a major concern and jojoba is known to flourish under controlled low water conditions. As such, jojoba wax esters were explored for skin care to reduce inflammation and sensitivity and to provide hydration over a 24-hr period.

Defining and Controlling Frizz

There is likely a variety of causes and contributors to the nebulous consumer term “frizz.” This article attempts to craft a universal definition and then progresses to further examine impacting factors. These discussions focus on methods for quantifying hair properties and assessing the positive impact of commercial hair care products.

beautiful Asian woman with radiant glowing skin

Testing Tactics in Skin: Evaluating Radiance and Texture

Hydrated, even-toned skin with a natural glow, all indicators of health, has gained popularity in the last decade. This article explores the meaning of skin radiance, its relationship to texture and various ways to measure this desired attribute.

CT2003_Holtz_850x425

Managing Adversities: Atopic Dermatitis and the Microbiome

The AD process and S. aureus provide targets for intervention, which can be explored in vitro as described here. Although not causative, there is a strong correlation between the severity of AD and density of S. aureus in the microbiome.

WomanEucalyptusSkinCare850x425

Lauder Findings on Sirtuins, Stress and Eucalyptus

New findings highlight the importance of sirtuins in skin cell activity, how they relate to environmental signals and circadian rhythm, plus the antioxidant efficacy of eucalyptus.

Page 1 of 4