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Section: Research > Literature/Data

Patent Picks— Foam Enhancement, Functionalized Polymers, Modified Sorbitan Siloxanes, Bacterial Cellulose Network and More for Cleansing

Chosen biweekly for their relevance to personal care, Patent Picks are taken from publicly available sources. This edition features technologies related to cleansing skin and hair.

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Study Shows How Eczema is Genetic

A study published in Genome Biology and Evolution found that atopic dermatitis (eczema) is likely to hitchhike a ride with mutated hornerin and make the skin disease genetic.

Exploring the Depths of Percutaneous Penetration

The Perspectives in Percutaneous Penetration (PPP) conference recently was held at the Palais des Congrès de La Grande Motte. Following are some highlights most relevant to the cosmetics and personal care industry.

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Rubbing Shoulders with Massage for Improved Penetration

Rubbing is a common application method for topical products, though evidence of its efficacy remains scarce. The present article reviews research in support of this application theory. It also identifies what investigation is still needed.

Cationic Peptides and Cell Penetration

Controversy surrounds how certain cationic peptides enter the cell.

Magnetism for Potential Delivery, Antioxidant Effects?

A recent study conducted at Harvard Medical School and the Wyss Institute of Biological Inspired Engineering induced magnetism in yeast cells, the implications of which suggest potential application in future delivery systems or potentially for antioxidant benefits.

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Study of Twins Correlates Aging with Genetics

While up to 40% of aging-related changes in skin are due to non-genetic factors, a recent study found a high correlation between the photodamage scores among both monozygotic (identical) and dizygotic (fraternal) twins.

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Don’t Count On Genetics, Sunscreens are the Best Bet

In a podcast with P&G scientists Frauke Neuser, Ph.D. and Rosemarie Osborne, Ph.D., Cosmetics & Toiletries learned about genetic studies in support of the Olay brand, and more. Following is an excerpt.

Skin Penetration of EGCG, Quercetin Examined

A recent study in Skin Pharmacoloy and Physiology examined the delivery of epigallocatechin-3-gallate and quercetin from green tea and Ginkgo biloba extracts into the skin from cosmetic formulations.

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EpigenCare Offers Personalized Skin Care via Epigenetics

The company matches consumers to existing skin care products based on their epigenetic profile and skin quality indicators, including aging and DNA damage.

Validating the Effectiveness of Rubbing on Percutaneous Penetration

The effect of rubbing on percutaneous penetration has long been questioned. Existing data regarding rubbing effects is sparse, and what is available is controversial at best. While some evidence suggests that rubbing increases absorption, others note the opposite. Further understanding of the rubbing effect on percutaneous penetration may offer a more complete picture in relation to the application of drugs, cosmetics and skin care.

Penetration of Cosmetics Into and Through the Stratum Corneum

The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.

Rapid Electrokinetic Patterning for Biological Analysis, Nanoassembly

Researchers at Purdue University have developed a rapid electrokinetic patterning technique using a laser and holograms to quickly position tiny particles for biological analyses or to create devices using nanoassembly.

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Epigenetics and Aging: A New Player in Skin Care

The cosmetics and skin care industry is constantly developing new products and technologies that aim to slow down the skin aging process. Epigenetic processes play an important role in skin aging. Several new cosmetic products target epigenetic mechanisms and have shown promising results as novel cosmeceuticals.

Penetration of Cosmetics Into and Through the Stratum Corneum

The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.

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Lipotec’s Peptide Regenerates Skin Using Epigenetics

Lipotec has launched PEPROAGETM peptide, which assists in leaving skin smoother, more radiant and visually rejuvenated. The peptide can be incorporated into any anti-aging formulation to help reduce skin regeneration taking place with age or in products designed to rejuvenate the skin.

Biobank Project Initiated for Genetics, Disease Studies

Funded by the Wellcome Trust, the Medical Research Council, the Department of Health and the Scottish Executive, the study is designed to examine the interaction of genes, environment and disease in half a million people.

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P&G, 23andMe Uncover Genetic Ties to Sensitive Skin

Research from P&G and 23andMe reveals new genetic associations underlying sensitive skin syndrome.

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