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Section: Research > Literature/Data

Formulating Focus: The Influence of Emollients on Skin Penetration

This column will discuss ways in which ingredients can positively affect the partition coefficient of the active between the formula and the skin. By carefully selecting the emollients used in a formulation, formulators can increase the delivery and clinical efficacy of a formulation without increasing the level of the active ingredient.

Formulating Focus: The Influence of Emollients on Skin Penetration

This column will discuss ways in which ingredients can positively affect the partition coefficient of the active between the formula and the skin. By carefully selecting the emollients used in a formulation, formulators can increase the delivery and clinical efficacy of a formulation without increasing the level of the active ingredient.

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The Genetic Relation Between Skin Tanning and Burning

Scientists recently investigated whether or not genetics can be linked to the propensity of skin to burn or tan, and how this connection may also explain people at risk to skin cancer.

The flutamide plus minoxidil solution was significantly more effective than minoxidil.

Flutamide Enhances Efficacy of 5% Minoxidil in Androgenetic Alopecia

Topical flutamide plus minoxidil solution was significantly more effective than minoxidil in improving hair density, hair thickness and patient satisfaction.

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Patent Pick: Conjugated, Penetrating Botulinum Toxin

Patent Picks are chosen by the editors from publicly available sources. Today's patent relates to a cell-penetrating peptide fused to a botulinum toxin recombinant protein, for cosmetic and other purposes.

Assessing the Safety of Parabens: Percutaneous Penetration and Risk Analysis

In cosmetics, parabens are widely used due to their low cost and efficacy. In recent years, however, some reports have claimed that these materials exhibit estrogenic activity, which has led to attempts to replace them in formulations. This article reviews penetration studies of parabens spanning the past 20 years to determine whether they pose a risk to human health.

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Vitis vinifera Leaf Extract Exhibits Epigenetic Protection In vitro

Grape and its extracts have long been known to impart anti-aging benefits, and recent work published in Molecular Biology Reports demonstrates just how—via epigenetics.

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Genetically Engineered Bacteria Produce a Rainbow of Natural Colors

While there are enormous regulatory hurdles to approving new colorants for cosmetic, food and pharma applications, this study represents progress in the search for naturally derived colors.

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Skin Pigment Genetics is More Complex at the Equator

New research published in Cell presents genetic findings related to skin pigment diversity and complexity, further supporting the trend for customizable skin care.

Study Uncovers Genetic Predispositions to Skin Cancer

Basal cell carcinoma is the most common cancer worldwide, with an annual incidence of 2.8 million cases in the United States alone. A recent study found 31 genetic markers for the disease, 14 of which were identified for the first time.

A Dermatological View—Percutaneous Penetration of Amino Acids

Skin care products containing amino acids often promote the benefits conferred on the skin by these molecules. Natural amino acids found in the skin have been found to improve the health of skin through antioxidation, membrane stabilization and increasing skin’s natural moisturizing factor (NMF).

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Tpl2's Major Role in the Genetics of Skin Cancer

Skin cancer is no joke, and that is why so many people are working to try and better understand it. Katie DeCicco-Skinner is one such person who is looking into the genetics of squamous cell carcinoma.

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Genetic Mutations Open Doors to Atopic Dermatitis

Atopic dermatitis may be caused by a single-gene mutation, according to new research published in Nature Genetics. Scientists believe the effects of the mutation could be partially corrected through glutamine supplementation.

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ZnO Nanoparticles Penetrate but Only Under These Conditions

Zinc oxide (ZnO) nanoparticles are a major component in sunscreens but their ability to permeate skin has remained undetermined. Recent work in Applied Biomaterials identifies the conditions under which they penetrate—notably, not in their nano form as they exist in sunscreens.

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Taking Shape: Genetic Facial Markers Discovered

Using novel 3D technology, researchers discovered 15 new genes that determine facial features, as published in Nature Genetics.

A recent study conducted by Bajaj Consumer Care Ltd, aimed to develop a method to measuring oil penetration into hair in correlation to hair thickness and tensile strength.

Study Correlates Oil Penetration into Hair with Tensile Strength

A recent study by Bajaj Consumer Care, Ltd., sought to identify a method to measure oil penetration into hair and how this correlates with hair thickness and tensile strength.

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[podcast] Author Commentary: Epigenetics in Cosmetics, with Paul Lawrence, Ph.D.

Today, Cosmetics & Toiletries has a special treat for you. Paul Lawrence, Ph.D., co-author on a new three-part article series, shares insights on the potential for epigenetics in cosmetics—not coincidentally, the topic of the series. Listen now!

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Massive Study Identifies Genetic Indicators for Skin Cancer Risk

The results of a massive study examining some 7,404 cases of squamous cell carcinoma in skin identified genetic associations with this disease, some for the first time.

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