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29 Results
Type: Article
Section: Research > Literature/Data
Literature/Data
Patent Picks— Foam Enhancement, Functionalized Polymers, Modified Sorbitan Siloxanes, Bacterial Cellulose Network and More for Cleansing
Chosen biweekly for their relevance to personal care, Patent Picks are taken from publicly available sources. This edition features technologies related to cleansing skin and hair.
Literature/Data
Study Shows How Eczema is Genetic
A study published in
Genome Biology and Evolution
found that atopic dermatitis (eczema) is likely to hitchhike a ride with mutated hornerin and make the skin disease genetic.
Event Coverage
Exploring the Depths of Percutaneous Penetration
The Perspectives in Percutaneous Penetration (PPP) conference recently was held at the Palais des Congrès de La Grande Motte. Following are some highlights most relevant to the cosmetics and personal care industry.
Methods/Tools
Rubbing Shoulders with Massage for Improved Penetration
Rubbing is a common application method for topical products, though evidence of its efficacy remains scarce. The present article reviews research in support of this application theory. It also identifies what investigation is still needed.
Actives
Don’t Count On Genetics, Sunscreens are the Best Bet
In a podcast with P&G scientists Frauke Neuser, Ph.D. and Rosemarie Osborne, Ph.D.,
Cosmetics & Toiletries
learned about genetic studies in support of the Olay brand, and more. Following is an excerpt.
Methods/Tools
Validating the Effectiveness of Rubbing on Percutaneous Penetration
The effect of rubbing on percutaneous penetration has long been questioned. Existing data regarding rubbing effects is sparse, and what is available is controversial at best. While some evidence suggests that rubbing increases absorption, others note the opposite. Further understanding of the rubbing effect on percutaneous penetration may offer a more complete picture in relation to the application of drugs, cosmetics and skin care.
Literature/Data
Penetration of Cosmetics Into and Through the Stratum Corneum
The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.
Literature/Data
Epigenetics and Aging: A New Player in Skin Care
The cosmetics and skin care industry is constantly developing new products and technologies that aim to slow down the skin aging process. Epigenetic processes play an important role in skin aging. Several new cosmetic products target epigenetic mechanisms and have shown promising results as novel cosmeceuticals.
Literature/Data
Penetration of Cosmetics Into and Through the Stratum Corneum
The penetration routes of substances through the stratum corneum and how these transport pathways function are becoming better understood. Despite this progress, however, the penetration mechanisms of cosmetic formulations remain mysterious. This overview presents current knowledge on the various pathways of penetration, and suggests that even if cosmetic formulations penetrate no deeper than the surface, their efficacy may still be optimal.
Literature/Data
Formulating Focus: The Influence of Emollients on Skin Penetration
This column will discuss ways in which ingredients can positively affect the partition coefficient of the active between the formula and the skin. By carefully selecting the emollients used in a formulation, formulators can increase the delivery and clinical efficacy of a formulation without increasing the level of the active ingredient.
Literature/Data
Formulating Focus: The Influence of Emollients on Skin Penetration
This column will discuss ways in which ingredients can positively affect the partition coefficient of the active between the formula and the skin. By carefully selecting the emollients used in a formulation, formulators can increase the delivery and clinical efficacy of a formulation without increasing the level of the active ingredient.
Literature/Data
Assessing the Safety of Parabens: Percutaneous Penetration and Risk Analysis
In cosmetics, parabens are widely used due to their low cost and efficacy. In recent years, however, some reports have claimed that these materials exhibit estrogenic activity, which has led to attempts to replace them in formulations. This article reviews penetration studies of parabens spanning the past 20 years to determine whether they pose a risk to human health.
Literature/Data
A Dermatological View—Percutaneous Penetration of Amino Acids
Skin care products containing amino acids often promote the benefits conferred on the skin by these molecules. Natural amino acids found in the skin have been found to improve the health of skin through antioxidation, membrane stabilization and increasing skin’s natural moisturizing factor (NMF).
Literature/Data
Genetically Engineered Bacteria Produce a Rainbow of Natural Colors
While there are enormous regulatory hurdles to approving new colorants for cosmetic, food and pharma applications, this study represents progress in the search for naturally derived colors.
Literature/Data
Study Correlates Oil Penetration into Hair with Tensile Strength
A recent study by Bajaj Consumer Care, Ltd., sought to identify a method to measure oil penetration into hair and how this correlates with hair thickness and tensile strength.
Literature/Data
Caprylyl Glycol/Phenethyl Alcohol Blend for Alternative Preservation of Cosmetics
In recent years, the safety of traditional preservatives has been called into question. Therefore, there is a need for alternatives that are effective, safe and sustainable—and that are non-controversial. In response, the present work investigates a mixture of caprylyl glycol and phenethyl alcohol, which is shown to provide antimicrobial activity in various skin and hair care formulations.
Literature/Data
Assessing the Safety of Parabens: Percutaneous Penetration and Risk Analysis
In cosmetics, parabens are widely used due to their low cost and efficacy. In recent years, however, some reports have claimed that these materials exhibit estrogenic activity, which has led to attempts to replace them in formulations. This article reviews penetration studies of parabens spanning the past 20 years to determine whether they pose a risk to human health.
Magazine
Fullerene Nanoparticles: Power Skin Penetration, Antioxidant Defense
Nanotechnology-based formulas can improve the behavior release of ingredients and their skin penetration. Fullerene nanoparticles, in particular, are useful for ROS scavenging. This review summarizes recent trends in fullerene-containing skin care.
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