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56 Results
Section: Research > Literature/Data
Literature/Data
Amorepacific Discovers Genetic Skin Barrier Regulator, Lesion Connection
During a Society for Investigative Dermatology e-poster session, Amorepacific shared research uncovering the role of EGR3 in skin barrier functioning and its connection with compromised skin.
Literature/Data
Caprylyl Glycol/Phenethyl Alcohol Blend for Alternative Preservation of Cosmetics
In recent years, the safety of traditional preservatives has been called into question. Therefore, there is a need for alternatives that are effective, safe and sustainable—and that are non-controversial. In response, the present work investigates a mixture of caprylyl glycol and phenethyl alcohol, which is shown to provide antimicrobial activity in various skin and hair care formulations.
Literature/Data
Assessing the Safety of Parabens: Percutaneous Penetration and Risk Analysis
In cosmetics, parabens are widely used due to their low cost and efficacy. In recent years, however, some reports have claimed that these materials exhibit estrogenic activity, which has led to attempts to replace them in formulations. This article reviews penetration studies of parabens spanning the past 20 years to determine whether they pose a risk to human health.
Literature/Data
Lauder and Sassone-Corsi Collaborate for Epigenetic, Circadian Research
The two laboratories will collaboratively explore the interaction between a newly identified micro-signaling molecule and other skin activities, including circadian machinery.
Skin Care
Hydrophilic vs. Lipophilic Moisturizers: Penetration Profiles and SC Water Distribution
A recent studying examining study published in Experimental Dermatology examined hydrophilic and lipophilic moisturizers, finding that they have similar penetration profiles but different effects on stratum corneum (SC) water distribution in vivo.
Literature/Data
K18 Granted Patent for Hair Fiber-penetrating Peptides
San Francisco-based indie brand K18 has been awarded a patent for peptides that can penetrate the hair fiber to improve its strength and hydrophobicity, and that have more affinity to hair keratin than previously developed peptides.
Magazine
Fullerene Nanoparticles: Power Skin Penetration, Antioxidant Defense
Nanotechnology-based formulas can improve the behavior release of ingredients and their skin penetration. Fullerene nanoparticles, in particular, are useful for ROS scavenging. This review summarizes recent trends in fullerene-containing skin care.
Literature/Data
Over the Top: Histone Deacetylase Inhibitors for Restorative Epigenetic Skin Care
The skin care industry has begun to explore epigenetics to ameliorate skin conditions. Within this field, histone deacetylase inhibitors (HDACis) are of interest thanks to their potent anti-inflammatory and other anti-aging effects. This article reviews their activity and utility.
Literature/Data
From Urea/Ammonium Lactate Combinations to Penetration Pathways in Hair
Gloor et al. have raised the question "Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone?"
Literature/Data
[podcast] How Nutrition Translates to Beauty, Part V: Epigenetic and Microbiome Factors
In relation to nutricosmetics, how does the microbiome come into play? What about epigenetics? This five-part podcast series with Zoe Diana Draelos, M.D., and Alan Dattner, M.D., considers the impact of nutrition on beauty. Here in part V, we consider these and other external factors.
Literature/Data
Patent Picks—Flavonoids, Genkwanin and Sakuranetin, Heat Shock Proteins and More
Chosen biweekly for their relevance to personal care, Patent Picks are taken from publicly available sources. This edition features patents related to anti-aging skin care technologies.
Method/Process
A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.
Literature/Data
Caprylyl Glycol/Phenethyl Alcohol Blend for Alternative Preservation of Cosmetics
In recent years, the safety of traditional preservatives has been called into question. Therefore, there is a need for alternatives that are effective, safe and sustainable—and that are non-controversial. In response, the present work investigates a mixture of caprylyl glycol and phenethyl alcohol, which is shown to provide antimicrobial activity in various skin and hair care formulations.
Safety/Stability
Research Reviews Non-penetrating Sunscreen Vehicles, Looks to Jojoba
Several "carriers for the future" were highlighted, such as lipid carriers, cyclodextrin derivatives, encapsulation approaches and non-penetrating sunscreens incorporating UV filters and jojoba oil conjugates.
Method/Process
A High Throughput Method to Predict Skin Penetration and Screen Topical Formulations
This work studies the applicability of a 96-well-based skin-mimetic artificial membrane permeability model to differentiate between topical pharmaceutical and cosmetic formulations. Results are compared with data obtained from in vitro Franz cell permeability measurements and reveal the applicability of this method to assess cosmetic formulation permeation and speed the discovery process.
Literature/Data
Patent Picks— Electromagnetic Radiation, Omentum, Plant Extracts, Growth Factors, Gingerone and More
Chosen biweekly for their relevance to personal care, Patent Picks are taken from publicly available sources. This edition features patents related to active ingredients for skin benefits and to address hair loss.
Literature/Data
Patent Picks—Improving Differentiation, Penetration and Optical Benefits in Skin Care, and More
Patent Picks are compiled by the editors from publicly available sources. This edition features recent inventions related to sensory, repair and formulating strategies for skin care.
Consumers/Market
Expert Opinions on Responsible Beauty: Ocean Sourced, Fermented, Planet Positive, AI Enabled and Consciously Cultivated
“Toxin-free,” zero impact, fair trade, biodegradable, etc., are all facets of the responsible beauty movement. This month, we asked several industry experts to weigh in about the meaning of responsible beauty and its current and future market directions.
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