Patent Picks are compiled by the editors from publicly available sources. This edition features recent inventions related to sensory, repair and formulating strategies for skin care.
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Patent Picks are compiled by the editors from publicly available sources. This edition features recent inventions related to sensory, repair and formulating strategies for skin care.
Acrylic film-former, tackifier and ester for shine, wear, feel and texture
U.S. Patent Application 20140242014
Publication date: Aug. 28, 2014
Assignee: L'Oréal
According to this patent, there remains a need for cosmetic compositions having improved shine, wear, feel and texture characteristics. The present invention addresses these needs. It comprises at least one polyol(s) ester and fatty diacid dimer or an ester thereof; at least one acrylic film-forming agent; and at least one tackifier.
Nicotinic acid adenine dinucleotide phosphate for keratinocyte differentiation
U.S. Patent 8816065
Publication date: Aug. 26, 2014
Assignee: DAMY Chemical Co., Ltd.
The present invention relates to the use of nicotinic acid adenine dinucleotide phosphate (NAADP), or a derivative thereof, for promoting the differentiation of keratinocytes into fibroblasts. Disclosed are pharmaceuticals or cosmetics containing NAADP for regenerating and improving the skin barrier, or preventing, improving or treating stratum corneum disorders, such as psoriasis or atopy. Specifically, the present inventors found that NAADP promotes intracellular calcium release as calcium signaling molecules in the keratinocytes, and has an effect of increasing expression of involucrin, keratin 1 and keratin 10—differentiation markers of the keratinocytes.
Arginine heteromers for improved skin penetration
U.S. Patent 8815954
Publication date: Aug. 26, 2014
Assignee: Revance Therapeutics, Inc.
Diclosed herein are arginine heteromers, which have an improved ability to penetrate and provide beneficial effects for the health and appearance of skin. According to the inventors, topically applying arginine chemically bound to a second (non-oligoarginine) compound increases its transepithelial delivery through a combination of increased solubility and flux across the skin. The described arginine heteromers can add other complementary or beneficial properties beyond those that are arginine-related.
Desaturases and process for the production of polyunsaturated fatty acids
U.S. Patent 8822662
Publication date: Sept. 2, 2014
Assignee: BASF Plant Science Company GmbH
This patent relates to polynucleotides from Cochliobolus heterostrophus C5, Cyanothece sp. CCY0110, Mycocentrospora acerina and Hyaloperonospora parasitica, which code for desaturases and can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms that comprise the polynucleotides; to the polypeptides encoded by the polynucleotides; to antibodies against the polypeptides; and to production processes for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions, as well as their use as drugs, cosmetics, food supplements and more.
Odor-free isoalkane oil body mixture
U.S. Patent 8821842
Publication date: Sept. 2, 2014
Assignee: BASF SE
This invention describes saturated hydrocarbons that are suitable as oil bodies for cosmetic and pharmaceutical compositions; in particular, they exhibit no intrinsic odor. It surprisingly has been found that an isoalkane mixture with an average degree of branching provides such a benefit. The invention specifies an isoalkane mixture whose 1H NMR spectrum in the region of a chemical shift δ of from 0.6 to 1.0 ppm, based on tetramethylsilane; and preferably has a surface integral of from 35 to 55%, based on the total integral surface.
Low-foaming, non-sticky copolymers for spray applications
U.S. Patent 8821841
Publication date: Sept. 2, 2014
Assignee: BASF SE
Disclosed in this patent are aqueous skin or hair preparations that include at least one polymer, in copolymerized form; at least one ester of (meth)acrylic acid; at least one olefinically unsaturated, free-radically polymerizable anionogenic or anionic compound; at least one free-radically polymerizable, olefinically unsaturated, urethane-group-containing compound without silicone groups; and, if appropriate, further free-radically polymerizable compounds. One object of the present invention was to provide polymers for skin or hair preparations that can readily be formulated as pump or aerosol spray in solvents or solvent mixtures with an increased water fraction, whose formulations form small uniform droplets and, during and after application, have the lowest possible tendency for foaming. Additionally, the films formed should not be sticky and should have good mechanical properties.
Composition for optical and viscosity-modifying benefits
U.S. Patent Application 20140242134
Publication date: Aug. 28, 2014
Assignee: Conopco, Inc./Unilever
According to these inventors, there is a need for cosmetic compositions that, in a non-permanent way, modulate the optical appearance of skin in a predictable way, especially over time, after application to the skin. There is also a need for said compositions to feel non-sticky. The present invention was designed to meet these needs. It comprises a water-in-oil emulsion including hydrophobically modified particles, amino functionalized silicone, and water; it further comprises a viscosity-modifying agent and optical light-modifying agent.
Vitamin K analogs for anti-inflammatory benefits
U.S. Patent 8815953
Publication date: Aug. 26, 2014
Assignee: Spectrum Pharmaceuticals, Inc.
This invention provides topical formulations containing a vitamin K analog, e.g., menadione, which deliver a uniform, therapeutically effective concentration of the vitamin K analog to the skin. These formulations are useful for the treatment and prevention of dermatological conditions associated with inflammation, particularly dermatological conditions resulting from anti-epidermal growth factor receptor (anti-EGFR) therapies.
