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Ergothioneine Shown to Protect Telomeres Under Stress

Research from the Journal of Dietary Supplements suggests that under oxidative stress, ergothioneine treatment can maintain significantly longer telomere lengths.

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Kao Finds Hands Hold Lactic Acid-based Defense Against Microbes

Kao researchers have uncovered innate lactic-acid based defenses in hand sweat that protect some individuals better than others against bacteria and viruses such as the common cold and influenza.

Results showed that 7.7% of samples were non-compliant with legislative requirements due to a missing or false declaration of allergenic fragrance compounds.

EDQM Finds Allergenic Fragrances in ‘Perfume-Free’ Cosmetics

Results showed that 7.7% of samples were non-compliant with legislative requirements due to a missing or false declaration of allergenic fragrance compounds.

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[video] Cosmetics R&D Vlog: Spot-on Connections Between Nerve Fibers and Pigmentation

Intracutaneous nerve fibers could be a key factor for determining age spot-prone sites on the face. Kazuki Nakayama, of POLA Chemical Industries, explains, in this Cosmetics R&D Vlog entry.

Sytheon announced it has been granted a U.S. patent for the skin lightening ingredient Synoxyl AZ, which also has antioxidant, anti-inflammatory and anti-aging properties.

Sytheon Obtains U.S. Patent on Synoxyl AZ

Sytheon announced it has been granted a U.S. patent for the skin lightening ingredient Synoxyl AZ.

Bisphenols have been implicated in disruptions to the growth, reproduction and development of aquatic organisms.

Endocrine Effects, Environmental Risk Feedback Sought for Dibutyl Phthalate, Bisphenols

The Jan. 5, 2021, deadline draws near for comments on dibutyl phthalate's reported endocrine-disrupting effects. In addition, German authorities are calling for evidence regarding the environmental risks of bisphenols.

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Aging Out: Telomere Shortening, Cell Senescence Reversed by Hyperbaric Oxygen Therapy

Research published in the journal Aging indicates, in isolated blood cells, that hyperbaric oxygen therapy could increase telomere length and improve senescence, pointing to potential anti-aging applications.

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Kao Defies Aging with Laugh Line-tightening Tech

Kao's technology reduced the conspicuousness of nasolabial folds through the application of a film-former that shrinks upon drying. This decreased fold depth by an average of 1 mm.

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De-Ironizing Inducer Pre-empts Free Radicals, Slows Aging in Menopausal Skin

A recent white paper published by Xi Huang, Ph.D., presents a "better than retinol" approach to pre-empt the production of free radicals in mature skin by targeting excess iron. Promising results from clinical trials will be published in March 2021.

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Sinapic Acid Esters Could Replace Octinoxate in Sunscreens

Research published in Antioxidants highlights a potential alternative to octinoxate for UVB protection and antioxidant effects: p-hydroxycinnamic esters from naturally occurring sinapic acid.

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[video] Cosmetics R&D Vlog: 'Hair-raising' Insights on Anti-aging

Award-winning research from Shiseido, presented by Tomonobu Ezure, Ph.D., during IFSCC 2020, reveals the hair muscles provide structural support to prevent skin sagging. Learn more from this vlog entry.

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Resveratrol Analogue and Equol Revive Menopausal Skin

A decrease in estrogen during menopause negatively affects the skin, according to a study published in Dermatology and Therapy, but a novel resveratrol analogue and the isoflavonoid equol offer new hope.

The review examines the impact of the circadian rhythm on stem cells in relation to regeneration in both young and old skin.

How the Circadian Cycle Regulates Skin Regeneration: A Review

A recent review published in the Journal of Investigative Dermatology explores how skin regeneration follows a circadian cycle.

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Benzalkonium Chloride Demonstrates Alcohol-free Antimicrobial Efficacy

Benzalkonium chloride has recently drawn interest for the formulation of hand sanitizers due to its availability and alcohol-free efficacy. Here, we review two studies showing its virucidal and bactericidal activities.

Results showed that in healthy skin, the acyl chain of ceramide N-(tetracosanoyl)-sphingosine was in the central and outer layers, while the sphingosine chain was only in the middle of the outer layers.

Research Uncovers Positioning of Sphingosine Chains in Healthy Skin

Research published in Langmuir has uncovered the positioning of sphingosine chains in the stratum corneum, providing insight into how ceramides should be arranged in healthy skin.

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Comparatively Speaking: Crossmodal vs. Lineal Perception

Lineal perception relates to a direct line between a stimuli and a single sensory interpretation. Crossmodal perception refers to responses and interpretations of various senses to a stimulus, offering product developers opportunities to create novel consumer experiences.

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Colorescience Shows Iron Oxides Extend Blue Light Protection

A Colorescience product containing iron oxides, titanium dioxide and zinc oxide was shown to attenuate light in the HEV (blue) spectrum. Results were published in the Journal of Cosmetic Dermatology.

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AI-aided Pathways Effectively Synthesize Naturally Occurring Compounds

AI-aided technology continues to find utility in cosmetics R&D. A recent paper published in Nature provides an example, showing the efficacy of computational synthesis planning for naturally occurring compounds.