Sinapic Acid Esters Could Replace Octinoxate in Sunscreens


Research published in Antioxidants has uncovered the UVB-filtering and antioxidant capabilities of p-hydroxycinnamic esters derived from naturally occurring sinapic acid.

These materials are proposed as octinoxate replacements, whose reef-friendly status has recently been called into question. In fact, as previously reported, in 2021, the State of Hawaii will ban the sale of sunscreens containing this organic UV filter. There is thus a pressing need for alternative UV filters offering safety and efficacy for users and the environment.

See related: Key West Joins Hawaii in the Ban of Octinoxate and Oxybenzone

In this context, these authors point to p-hydroxycinnamic esters derived from naturally occurring sinapic acid via Knoevenagel–Doebner condensation. According to the article abstract, a wide library of these materials is available and they show promising UVB protection and antioxidant efficacy. Details of their synthesis and UV/antioxidant testing are disclosed in the full open access article.

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