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527 Results
Section: Testing
Sun Protection
In Vitro and In Vivo Offered for Sunscreen Testing
Laboratoire Dermscan and HelioScreen Labs are combining their skills to offer a complete new in vitro / in vivo service in the field of sunscreen testing.
Animal Alternatives
Comparing Methods to Measure Porcine Skin Integrity In Vitro
To confirm the integrity of porcine ski prior to penetration tests, published studies show that measuring transepidermal water loss, transdermal electrical resistance or caffeine penetration levels are often chosen techniques. New results demonstrate that
Literature/Data
Industry Insight: Seeing Through Layers of Skin Care Complexity
"With today’s advances in
omics
, generally ceramidomics, proteomics or lipidomics, we understand much better the complexity of area lipids in the stratum corneum; not only for body skin, but also for the face," says Tony Rawlings, Ph.D., in this exclusive interview.
Animal Alternatives
Industry, NGOs Claim REACH Amendments Could Increase Animal Testing
Industry and NGOs are calling out the European Commission's amendments to REACH to clarify animal testing requirements, highlighting how they likely will increase the use of animals.
Safety/Stability
[podcast] EWG vs. the Industry on Cosmetic Ingredient Safety
On the surface, this seems like a story about an activist group stirring up unnecessary fear to target an "unregulated" industry. And a self-regulated industry allegedly putting dollars ahead of safety. But the reality is actually much deeper and philosophical in nature. Listen now!
Literature/Data
Antioxidant, Anti-inflammatory Effects of CBD Confirmed in Keratinocytes
A study published in the
Journal of Natural Products
confirms the mechanism through which cannabidiol (CBD) exerts antioxidant and anti-inflammatory actions in human skin keratinocytes.
Method/Process
Moisturizer Penetration in Skin Revealed via Low-coherence Inferometry
Research published in the Russian journal
Engineering
describes a method to measure the penetration of gel moisturizers in skin in vivo via low-coherence interferometry.
Sun Protection
Interpretation of SPF In vivo Results: Analysis and Statistical Explanation
Methods for determining SPF in vivo are based on a biological response by human skin. To overcome intrinsic variation in these methods, large numbers of volunteers and statistics are required; however, these concepts are often poorly understood or worse, misinterpreted. This article discusses how these values should be interpreted and explains what they mean to formulators.
Sun Protection
Interpretation of SPF In vivo Results: Analysis and Statistical Explanation
Methods for determining SPF in vivo are based on a biological response by human skin. To overcome intrinsic variation in these methods, large numbers of volunteers and statistics are required; however, these concepts are often poorly understood or worse, misinterpreted. This article discusses how these values should be interpreted and explains what they mean to formulators.
Companies
Croda to Increase Global Reach and Innovation with Lab Expansions
Croda lab expansion and renovation project at North American HQ adds innovation, education and efficiencies.
Actives
Infusing New Life into an Old Reliable Skin Treatment: Retinaldehyde
Retinaldehyde is suitable for many skin care applications, and when combined with other substances becomes even more versatile. One of its newest topical delivery systems provides multifunctional opportunities.
Efficacy
Industry Insight: Testing the Most Efficient Color Shampoo/Conditioner Duos
In this "Industry Insight," Sabina Wizemann, senior chemist of the Health, Beauty and Environmental Sciences Lab at the Good Housekeeping Institute has evaluated shampoo and conditioner pairs to identify the best performers for hair dye retention. In a recent interview, she explained how she tests these products, analyzes their efficacy and claims, and which duos exemplified the highest efficacy, compared with other products.
Regional
Cosmetovigilance and Safety Assessment in the World of Active Ingredients
It can be deduced from today's scientific literature that countless ingredients have been developed with the intent to alter the structure and function of human skin. This raises important questions in terms of how these products should be regulated and what types of safety standards they should be held to.
Testing
Fighting AGEs Formation: Upcycled Artichoke Inhibits Glycation, Increases Skin Firmness
Upcycling organic waste into cosmetics has been of interest for the growing sustainability trend—and artichoke, in particular, demonstrates anti-aging activities. Described herein is the development of an upcycled artichoke byproduct, which was tested for effects on skin glycation and elasticity.
Efficacy
Industry Insight: Probing Deeper to Further Skin Aging Research
Johnson & Johnson can see the future—of skin aging, that is. How? Using a novel imaging technique. Tracy Wang, Ph.D., describes it here, in an adaptation from our recent podcast interview.
Literature/Data
Researchers Develop Invertebrate Alternative In vivo Skin Corrosion Test
Work published in Environmental Pollution describes an invertebrate alternative in vivo skin corrosion test that reportedly is more sensitive to acids and alkalis than traditional skin models.
Claims/Labeling
Translating Data into Claims and Interpreting Regulations: Science vs. Marketing
Substantial evidence, which the FDA requires to support claims for drugs, is applicable to personal care, especially considering the pharmaceutical direction products have taken. The present article considers whether the industry is benefiting from marketing without assuming the responsibility for potential effects. In addition, it considers the limitations of in vitro and in vivo test models.
Method/Process
Dermal Absorption Guidelines for Cosmetic Ingredients: An In Vitro Method
Ex vivo skin absorption studies measure the penetration and permeation of a compound to assess its safety, and can assist the formulator in increasing product efficacy and reducing toxicity. This review analyzes the currently available guidelines published by four major regulatory organizations to clarify important milestones in study design, data analysis and interpretation.
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