Current Issue cover

Recent in Testing (page 30 of 36)

Testing Sun Protection Factor in Skin

There are various test methods set by global governing bodies for SPF protection, but this article will discuss the five time-point internationally approved ISO 24444 method.

Solar Flair

If like me, you’re just daydreaming of the beach, this collection of articles will enlighten you with its focus on sun protection, SPF testing, damage repair and more.

Image Processing and Analysis to Evaluate the Effects of Porous Polyamide Microspheres in Cosmetics

Described here is an image processing system that compensates for changes in illumination and volunteer position, and two algorithms to quantify skin texture and wrinkles. These methods evaluate skin parameters from a single image without contacting skin. Their abilities are demonstrated here in evaluations of the benefits of porous polyamide ultra-fine powders on skin texture and gloss.

In vitro/vivo SPF Correlation and Repeatability According to Substrate

This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.

Testing SPF 15–100, Indoor vs. Outdoor

Lab tests on sunscreens show it takes more energy to produce mild erythema on protected skin than unprotected skin. Yet the FDA questions the need for SPFs higher than 50. In response, two outdoor studies were conducted using commercial products to challenge standing premises and determine if there is a measurable difference in an SPF 100 and SPFs of 50 or less.

Testing Sun Protection Factor on Skin

There are various test methods set by global governing bodies for SPF protection, but this article will discuss the five time-point internationally approved ISO 24444 method.

Detecting Estrogenic Endocrine Disruptors in Personal Care Products and Supplements

Endocrine disruptor chemicals (EDCs) are a class of chemicals that has raised alarm for being linked to a wide variety of detrimental effects on human and wildlife populations, e.g., cancers, precocious puberty and obesity. Thus, there is a need to test personal care products and supplements for EDCs, which can be accomplished using the validated bioassay described here.

CeeTox Inches Closer to Validating Non-Animal Skin Allergy Assay

CeeTox has reported positive results from the recent phase of a PETA-funded validation study performed by the Flemish Institute for Technological Research (VITO)’s Applied BIO & Molecular Systems (ABS) team.

Mature and Immature Corneocyte Detection Force Distance Curves vs. Microfluorometry

Here, the author compares two methods to determine the maturity of corneocytes based on their cross-linking that could be used to evaluate the anti-aging effects of molecular agents. The first utilizes microfluorometry, while the second involves F-D curves generated via contact mode AFM. Both methods successfully detected differences in mature or immature corneocytes with 95% confidence.

Measuring Hair Strength, Part I: Stress-Strain Curves

This article is the first in a series that will address the approaches of measuring the “strength” of hair and quantifying the manner by which this property may be altered. Specifically, it will begin with the generation of stress-strain curves through the use of constant rate extension experiments.

Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing

Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.

Testing Tactics—Consumer vs. Scientific Language: Relating In vivo to In vitro

It should perhaps go without saying that consumer products are sold using consumer language. Market researchers and consumer scientists spend a great deal of time studying their target audience and learning this vocabulary, which subsequently allows the recounting of product benefits in the same terminology.

Can't find what you're looking for? Try searching, or looking through past issues.