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Section: Testing > Method/Process

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Ceramides in Skin Stress: Ultraviolet, Tape Stripping, and Crowding

Stress induces changes in the ceramide content of the skin, and may lead to compromised barrier function or skin diseases. Skin has ways of responding to these stresses, as we review here in the case of skin stressed by tape stripping, organic solvents, overcrowding, and ultraviolet (UV) irradiation.

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[podcast] CAS9 and CRISPR Technology: Implications for Cosmetics?

"CRISPR, in my mind, is like a molecular GPS. . .People just type in some short array sequence, essentially an address, to find the target. Upon binding to the target, a pair of molecular scissors cuts the DNA and performs a repair to modify the DNA sequence."

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Blue Diamond Launches Pure Oil for Health and Beauty

To provide beauty consumers with a pure oil blend, Blue Diamond Almonds has introduced 100% pure sweet almond oil, pressed from ripe, shell-free almonds grown in the orchards of California.

The VS450 is X-Rite's response to customers in the cosmetics industry that are looking for lab-to-production solutions.

Tools to Predict, Assess and Standardize Successful Color Cosmetics

Cosmetic companies have borrowed quality control methods from other industries that have product attributes such as color, gloss and texture down to a science. Specialized in such areas, X-Rite has developed tools to enable cosmetic companies to predict future color trends as well as set standards by which future cosmetics will be benchmarked.

In vitro/vivo SPF Correlation and Repeatability According to Substrate

This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.

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Testing Tactics: Approaches to Measure Scalp Comfort and Care

This article describes examples of test methods beyond standard skin hydration, sebum and TEWL measurements being used help create scalp care products that address conditions such as inflammation, redness, dandruff, seborrheic dermatitis and more.

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Yield Stress Measurements for Personal Care, Part I: Definitions and Basics

The aim of this article series is to properly define and differentiate yield stress from high viscosity, as well as develop a method for assessing whether a sample has a yield stress. In addition, it will illustrate how to determine the amount of yield needed for a given application.

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12 Top Trends and Buzzwords in Beauty at In-Cosmetics 2025

Here's a quick rundown of the top trends in beauty ingredients and concepts we saw at In-Cosmetics Global 2025; and this is just a sampling.

A Dermatological View—Squamometry: An Early Predictor of Changes in the Skin Barrier

Squamometry is useful in identifying the low or subclinical irritation potential of substances even before any change in the TEWL can be measured.

Using Tissue Engineered Skin to Eveluate the Irritation Potential of Skin Care Products

Using tissue engineered skin to evaluate the irritation potential of skin care products.

Patent Picks—Imaging Skin, Simulating Eyelashes, Assaying Immune Response and More

This edition of "Patent Picks" features recently issued patents relevant to advances in testing for cosmetics R&D.

Photostability Test for Additional Sunscreen Claims, Part II: Calculations and Results

Proposed here is an in vitro method, based on UV transmission measurements at two irradiation doses, to test and rank sunscreens based on their photostabilities. This approach was used to assess some 107 sunscreens and shows how, by strictly controlling key parameters, comparisons between the photostabilities of products can be made, with potential for new label claims.

Patent Picks—Diffusion Profiling, Optical Tweezer, Fluorescent Microbe Detection and More

Patent Picks are taken from publicly available sources and cover recent patents issued, or applied for, in the cosmetic and personal care industries and relevant peripheral markets. This edition features methods and processes for analyzing and producing cosmetic products and materials.

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CBD in Effect: Correlating In vitro and Ex vivo Skin Benefits

Primary biological functions of the skin barrier, immune system, lipids, free radicals and extracellular matrix are, in fact, impacted by CBD, as a poster and podium presentation by Genemarkers at SCC Annual demonstrated.

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Turn Back Time: New Findings Suggest Science Could Potentially Reverse the Signs of Aging

It may finally be possible to turn back the clock. Using cellular reprogramming, scientists at the Salk Institute have found a way to reverse signs of aging.

Rapid Colorimetric Analysis of para-Phenylenediamine in Henna-based, Non-permanent Tattoo Color Mixtures

In some henna mixtures, para-phenylenediamine (PPD) has illegally been added and it is responsible for complications such as allergic contact dermatitis. While high-performance liquid chromatography has previously been used to detect PPD, a colorimetric method that is faster and portable, described here, has been developed. For product developers, this method can be used to evaluate henna plant extracts.

A Rapid and Sensitive In vitro Method to Ascertain Antioxidative Capacity*

New methodologies have recently been developed to determine antioxidant effects but they often require extensive training and are time-consuming to conduct. In the present article, however, the authors describe an in vitro method to detect the effects of antioxidant-containing formulations using photochemiluminescence to provide rapid, accurate and sensitive measurements.

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[video] Cosmetics R&D Vlog: Sensory Experience and Clinical Efficacy—Testing Insights

In this Cosmetics R&D Vlog entry, Rachel Grabenhofer, of Cosmetics & Toiletries, gained insights from Celine Marque and Cyril Messaraa, two testing experts of Ori-Derm/Oriflame, on sensory and clinical testing today—and in the future. Watch now.

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