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Section: Testing > Method/Process
Method/Process
In the Land of the Blind: Applying a Single-blind Study to Finished Products
Following positive feedback from a previous column on the placebo effect, Wiechers readdresses clinical study design in relation to cosmetic claim substantiation—this time discussing when to perform double-blind studies and when to perform single-blind studies.
Claims/Labeling
Translating Data into Claims and Interpreting Regulations: Science vs. Marketing
Substantial evidence, which the FDA requires to support claims for drugs, is applicable to personal care, especially considering the pharmaceutical direction products have taken. The present article considers whether the industry is benefiting from marketing without assuming the responsibility for potential effects. In addition, it considers the limitations of in vitro and in vivo test models.
Event Coverage
Alphorns, Cowbells, Magic and Gaming at IFSCC Zurich, part IV
The 23rd IFSCC Congress, held Sept. 21-23, 2015, reported “more facts and less illusions” to some 550+ delegates from across the globe at the forefront of cosmetic product innovation.
Event Coverage
Alphorns, Cowbells, Magic and Gaming at IFSCC Zurich, part II
The 23rd IFSCC Congress, held Sept. 21-23, 2015, reported “more facts and less illusions” to some 550+ delegates from across the globe at the forefront of cosmetic product innovation.
Claims/Labeling
Translating Data into Claims and Interpreting Regulations: Science vs. Marketing
Substantial evidence, which the FDA requires to support claims for drugs, is applicable to personal care, especially considering the pharmaceutical direction products have taken. The present article considers whether the industry is benefiting from marketing without assuming the responsibility for potential effects. In addition, it considers the limitations of in vitro and in vivo test models.
Animal Alternatives
NICEATM Calls for Scientific Experts and Data on Eye Testing
The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) is looking for scientific experts and data for a scientific review panel.
Skin Care
One Ingredient, Twice the Benefits for Pores and Age Spots
DSM has created a solution to benefit two skin problems at once. The company’s latest skin care ingredient helps eliminate facial pores and age spots simultaneously. Additionally, helps the skin look younger and improves appearance after the age of 30.
Event Coverage
Water Content, Nanoparticles and Skin Penetration in Brazil: Lindo Maravilhoso!
Water content, surfactants, thickeners, actives, nanoparticles and skin penetration were among the hot topics presented at the biennial XXI COLAMIQC congress of the Latin American and Iberian cosmetic chemists. Held May 14-16, 2013, in São Paulo, technical sessions were paired alongside the FCE Cosmetique exhibition and trade show for both the cosmetics and pharmaceuticals industries.
Method/Process
Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing
Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.
Method/Process
Hair Color Vibrance Factor to Characterize Shine and Color Intensity*
To evaluate the comprehensive effects of shine and color intensity in hair, a hair color vibrance factor has been developed to enable new claims for hair dye formulas and after-dye treatments. Experimental results described here show how varying the ingredients in shine spray and hair dye formulas affect this factor and correlate with subjective panelist assessments.
Method/Process
Testing Tactics: REACH and In vitro Alternatives: Skin Irritation Testing
Welcome back to a continuing discussion regarding the new Registration, Evaluation and Authorization of Chemicals (REACH) regulation and its impact on chemical testing. It is the purpose of this series of articles to provide an overview of these existing validated in vitro methods, as well as new methods that are being considered for validation.
Method/Process
Detecting Estrogenic Endocrine Disruptors in Personal Care Products and Supplements
Endocrine disruptor chemicals (EDCs) are a class of chemicals that has raised alarm for being linked to a wide variety of detrimental effects on human and wildlife populations, e.g., cancers, precocious puberty and obesity. Thus, there is a need to test personal care products and supplements for EDCs, which can be accomplished using the validated bioassay described here.
Method/Process
Fluorescence LSCM to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair
The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.
Method/Process
Detecting the Protective Power of a Hair Health Multi-peptide: An Integrated Approach
This work measures the antioxidant potential of a hydrolyzed cicer seed extract, a multi-peptide derived from chickpeas, to protect hair. Advanced methods such as FTIR, DCFH-DA assays, cyclic fatigue and DSC testing are combined for a comprehensive view.
Tech Transfer
[podcast] CAS9 and CRISPR Technology: Implications for Cosmetics?
"CRISPR, in my mind, is like a molecular GPS. . .People just type in some short array sequence, essentially an address, to find the target. Upon binding to the target, a pair of molecular scissors cuts the DNA and performs a repair to modify the DNA sequence."
Skin Care
Blue Diamond Launches Pure Oil for Health and Beauty
To provide beauty consumers with a pure oil blend, Blue Diamond Almonds has introduced 100% pure sweet almond oil, pressed from ripe, shell-free almonds grown in the orchards of California.
Sensory
Tools to Predict, Assess and Standardize Successful Color Cosmetics
Cosmetic companies have borrowed quality control methods from other industries that have product attributes such as color, gloss and texture down to a science. Specialized in such areas, X-Rite has developed tools to enable cosmetic companies to predict future color trends as well as set standards by which future cosmetics will be benchmarked.
Sun Protection
In vitro/vivo SPF Correlation and Repeatability According to Substrate
This work evaluates the impact of three different substrates on in vitro SPF measurements, and defines experimental conditions to improve their correlation with in vivo values. Evaluations of 32 products, shown here, led the authors to conclude that molded substrates improved repeatability and correlation with in vivo SPF values.
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