Search Cosmetics & Toiletries

Researchers Develop Non-animal, Dendritic-based Sensitizer Test

Researchers from the University of Aveiro, the University of Coimbra and the University Hospital of Coimbra have developed a dendritic cell-based test for skin sensitizers that can serve as an alternative to animal testing.

Appointment of Commissioner Borg May Jeopardize Animal-alternative Test Progress

Cosmetics Europe recently urged the industry to oppose the appointment of Tonio Borg as Health Commissioner, as his "commitment to conclude the introduction of the March 2013 [animal testing] ban without addressing scientific reality or consumer needs is a great concern."

EMDMILL-lg

Non-animal Transdermal Diffusion Model Testing for Cosmetic Actives and Formulations

Experience the unmatched predictability of Strat-M membrane—a synthetic, non-animal based model* for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Permeation Method Developed As Alternative to Franz Cell

Pion Inc. has introduced a test method that predicts the permeability of drugs and dermal formulations through the human skin without the cost and low throughput restrictions of the Franz cell chamber.

Compass—Best Foot Forward

From an insider’s view, safety testing is an assumed step in the development of any product on the market. This puts the pressure on analytical and quality control efforts behind the scenes to ensure that ingredients and products meet or exceed expectations. In doing so, theoretically, no one else has to give it a second thought. For those who must give it considerable thought, this edition features two articles on testing, among other topics.

NICEATM Calls for Scientific Experts and Data on Eye Testing

The National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) is looking for scientific experts and data for a scientific review panel.

General Assembly Discusses Endocrine Disruptors, Nano, Animal Alternatives and More

Cosmetics Europe—The Personal Care Association, formerly Colipa, held its annual General Assembly in Brussels, Belgium in June 2012. The scientific forum discussed topics of interest in EU legislation such as The Cosmetics Regulation, which was set to replace the Cosmetics Directive on July 11, 2013.

A Synthetic Tissue-based In vitro Ocular Irritation Assay

The testing of personal care products for ocular irritancy ensures their safety, proper labeling and consumer satisfaction. In relation, there is a current demand for animal-alternative tests. Thus, described here is a method using synthetic tissue to test for mild, moderate and severe ocular irritation, including data validating this method as an effective means to screen products.

Calling All Chemists, Formulators and Researchers

Are you sitting on a research “gold mine”? Get your work published! Cosmetics & Toiletries magazine is interested in your research as it pertains to cosmetics and personal care R&D.

EPA, L'Oréal Collaborate to Build Animal-Alternative Test Methods

The US Environmental Protection Agency (EPA) and global cosmetic manufacturer L’Oréal announced a research collaboration to develop animal-alternative toxicity tests to ensure product safety.

ICCVAM Recommends Non-animal Endocrine Disruptor Screening

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) has recommended a non-animal test method to identify estrogen agonist and antagonist activity. In addition to recommending the test, ICCVAM also found the method to provide a number of benefits over the method currently employed in the United States.

Public Comments Requested for Development of NICEATM-ICCVAM 2013-2017 Five-Year Plan

NIEHS and NICEATM invite public comments that can be considered by the ICCVAM and the agencies' program offices in updating the NICEATM-ICCVAM 2008-2012 Five-Year Plan to develop the 2013-2017 Five-Year Plan.

Patch Testing vs. In Vitro Alternatives

A comparison between results of in vitro and in vivo testing on a selection of personal-care products begins to establish a validation database for in vitro product safety testing.

SCoutech Patents Ex Vivo Real Skin Model

SCoutech, a joint venture between Symrise AG and Cutech Srl, has received a patent on its ex vivo real skin model that reportedly bridges the gap between in vitro and in vivo testing of anti-aging products.

Colipa and EU Kick-off Animal Alternative Initiative

Safety Evaluation Ultimately Replacing Animal Testing (SEURAT), a research initiative funded by the European Union's Health Programme and Colipa, has gotten underway with a kick-off meeting, held March 1-3, 2011, in Cascais, Portugal.

ICCVAM Recommends Ocular Safety Tests for Cosmetics and Other Products

Four test method evaluation reports are now available from ICCVAM that provide recommendations for performing eye safety testing more humanely, and for developing and using non-animal test methods and strategies. Among these reports, ICVAAM has recommended that a cytosensor microphysiometer (CM) test method may be used to screen surfactant-containing formulations such as personal care products for the ability to cause permanent or severe eye injuries.

Patent Picks—Imaging Skin, Simulating Eyelashes, Assaying Immune Response and More

This edition of "Patent Picks" features recently issued patents relevant to advances in testing for cosmetics R&D.

Researchers Advance Animal-alternate Test for Skin Sensitization

Researchers at the National Institute for Occupational Safety and Health and Portland State University have developed an animal-alternative test method to assess the potential for chemicals in consumer products to cause skin allergies.