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EU Regulation Update: Tackling the Animal Testing Ban

The European Federation for Cosmetic Ingredients (EFfCI) has developed an approach for its members to address animal testing bans imposed by the 7th Amendment to the EU Cosmetics Directive.

Microfluidic Testing for LLNA Replacement

The Hurel Corp. has developed a microfluidic, non-animal alternative to the LLNA and it has partnered with L’Oréal to make this approach a reality—in the form of a chip.

Researchers Mimic the Lymphatic System in Animal Alternative Chip

A chip created by L'Oréal and Hurel Corp. is designed to replace the local lymph node assay, a test often performed on cosmetic raw materials. In addition to saving animals, the chip is also said to be less expensive than animal testing. Hurel developed the working microfluidic portion of the chip.

Strong, Self-healing Hydrogel Created for Tissue Engineering

Researchers from the University of Tokyo have created a strong, self-healing hydrogel with applications in tissue engineering and drug delivery. The material incorporates a binder made from long chains of polyethylene glycol, an ingredient commonly used in skin care.

EU Regulatory Update: Recast of the Cosmetics Directive Published

Regulation (EC) No 1223/2009 was published on Dec. 22, 2009 with the intent to simplify rules and procedures related to the marketing of cosmetic products, a need resulting from different implementations of the Cosmetics Directive.

ECVAM Calls for Testing Experts

The European Centre for the Validation of Alternative Methods (ECVAM) is renewing its scientific advisory structure and is calling for life sciences experts interested in joining its ESAC or EEP groups.

Comparing Methods to Measure Porcine Skin Integrity In Vitro

To confirm the integrity of porcine ski prior to penetration tests, published studies show that measuring transepidermal water loss, transdermal electrical resistance or caffeine penetration levels are often chosen techniques. New results demonstrate that

Virtually Real

This edition of C&T magazine takes a closer look at alternatives to animal testing with Oborska’s review of existing and pending methods. In addition, the author discusses the complexity of the process to validate alternative test methods.

Alternatives to Animal Testing: A Review of Trends and Perspectives

Alternative test methods have the potential to reduce animal testing; however, the extent to which in vitro methods can be replaced is questionable. This article summarizes validated alternatives to test the safety of cosmetic ingredients. It also illustrates how great a challenge it is to devise a proper alternative method.

Using Tissue Engineered Skin to Eveluate the Irritation Potential of Skin Care Products

Using tissue engineered skin to evaluate the irritation potential of skin care products.

ECVAM Approves Harmonized Lymph Node Assay Standards

ECVAM's Scientific Advisory Committee has endorsed the scientific validity of the harmonized ECVAM performance standards for the Local Lymph Node Assay.

Oxford Neurosurgeon Supports Animal Testing for Cosmetics

An Oxford, UK-based neurosurgeon who was one of the first scientists to publicly support the use of animals in medical research also condones their use to test cosmetics.

Framework Adopted from Animal Alternative Cooperation

A framework has been adopted to increase international cooperation, collaboration and communication on alternative test methods.

NICEATM Requests Info on the Murine Local Lymph Node Assay

The US National Toxicology Program (NTP), Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) has requested comments, nominations of scientific experts and submission of data on the murine local lymph node assay.

India Looks to Reduce Animal Testing

Reducing animal use for testing drugs and cosmetics was the focus of a recent congress held in Chennai, India.

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Ex Vivo Porcine Developed as Alternative to Animal Testing

Symrise and Cutech Srl have developed a new skin model out of pig skin as an alternative to animal testing.

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EVCAM Releases 61st Workshop

The European Centre for the Validation of Alternative Methods (EVCAM) has released its 61st report of a series of workshops.

EU and US Discuss Animal Testing

A framework has been established between the European Union (EU) and the United States that is expected to produce greater cooperation in the cosmetic and personal care industry.