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From Urea/Ammonium Lactate Combinations to Penetration Pathways in Hair

Contact Author Charles Fox
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Skin and Skin Care
Gloor et al. have raised the question "Do urea/ammonium lactate combinations achieve better skin protection and hydration than either component alone?" Twenty subjects with healthy skin were treated with the following formulation for two weeks: drug-free W/O vehicle, 5% ammonium lactate (CAS 52003-58-4) in W/O vehicle, 5% urea (CAS 57-13-6) in W/O vehicle, 3% ammonium lactate + 3% urea in W/O vehicle, 5% ammonium lactate + 5% urea in W/O vehicle.

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