Patent Pick: 'Mustard' Skin Delivery


Patent Picks are chosen by the editors from publicly available sources. Today's invention relates to plasma membrane vesicles extracted from plants of the mustard family (Brassicaceae cruciferae) for epidermal delivery applications.

Brassicaceae cruciferae (mustard family) transport proteins from for skin delivery
U.S. Patent 9138487
Publication date: Sept. 22, 2015
Assignee: Consejo Superior De Investigaciones Cientificas

This disclosure refers to a procedure for obtaining plasma membrane vesicles derived from the Brassica plant, which are enriched in aquaporins and other membrane-transport proteins and could additionally contain other substances such as natural bioactive compounds, hygroscopic or chemical agents for pharmacological and therapeutic uses.

Specifically, the methodology for obtaining the plant-plasma membrane vesicles comprises: a) a first phase of stimulation (or elicitation), applying a combined process of both abiotic stress and a bioactive compound to the plant; and b) a second step of membrane vesicle extraction. In addition, the invention relates to a method for increasing these proteins of plant origin.

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