Clariant's Prunizen Targets Stress-Induced Hair Loss

Prunizen targets psychoemotional stress-triggered cortisol production known to weaken hair health. A clinical study of the active found anti-hair loss activity after 3 months.
Prunizen targets psychoemotional stress-triggered cortisol production known to weaken hair health. A clinical study of the active found anti-hair loss activity after 3 months.
Image source: Clariant Natural Ingredients

Clariant Natural Ingredients announced the launch of Prunizen (INCI: Not Provided), a natural “feel-good” active to fight stress-induced hair loss; improve hair vitality and density; and restore hair and scalp well-being.

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Prunizen is derived from Prunella vulgaris, an edible and traditional medicinal plant commonly known as “self-heal.” Prunizen utilizes the properties of Prunella vulgaris to help reduce cortisol production. As Clariant explains, in destressing the hair and scalp, the extract counteracts the stress-induced slowing of hair follicle growth; helps to prevent hair fallout; and protects the hair structure. It also improves the scalp’s well-being by increasing the release of oxytocin, a neurotransmitter that provides anti-stress effects.

According to Clariant, clinical tests have demonstrated the ingredient's positive effects in fighting stress-induced hair loss and visibly improving hair density in emotionally stressed people. After three months, the volunteers benefited from a 15% reduction in hair in the loss stage of the growth cycle, an 83% increase in hair quality and a 38% increase in hair volume.

Prunizen will be showcased at in-cosmetics 2022 in a sample formulation within Clariant’s Beauty Wizard concept, and will be featured during the event in the presentation, “Natural Actives to Tackle the Effects of Contemporary Stress,” on April 5.

“PES [psycho-emotional stress] is deeply detrimental to scalp and hair health because it triggers excessive production of the hormone cortisol. This provokes negative reactions such as accelerated hair loss, thinning, graying, scalp irritation and itching. It’s not possible to eliminate PES periods from people’s lives, but we are delighted to offer an herbal active proven to uniquely reduce stress-induced changes, which will support anti-hair-loss innovation and the growing role of hair care products in managing emotional strain,” said Alexandre Lapeyre, head of marketing and business development of Clariant Natural Ingredients.

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