Consistency is the very first property that anyone can feel in an instant while touching a cream or an ointment. It is not only the first subjective impression of a new formulation, but also defines spreadability and can have a significant impact on how long it is effective on the skin.
With a continuing drive to always find new ingredients and new formulations, analytical testing is more important than ever. Analytical testing allows you to find a new ingredient and keep the well-known consistency of an established product or a new formulation with even further improved consistency.
Even though we can all feel the consistency of creams, this is a subjective evaluation. Therefore, it is important to find a quick and reliable objective value that can be compared.
The PNR 12 measures the resistance a material provides against being pierced by a specifically shaped test body. The Penetration Unit (PU) is the consistency of a material expressed as distance in tenths of a millimeter that a specifically shaped test body vertically penetrates.
The U.S. Pharmacopeia convention doesn’t just describe in USP procedures how to measure the identity, quality and purity of medicinal or food ingredients but also consistency measurement via the penetration method for various samples such as petrolatum, carboxymethylcellulose sodium paste, microcrystalline wax, vaselinum album and more.
Anton Paar provides a wide range of testing equipment in accordance with pharmacopeia standards, including optional certification and PQP-S documentation to support implementation of the instrument in your laboratory.
General product information and more application reports can be found here.
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