Detecting Estrogenic Endocrine Disruptors in Personal Care Products and Supplements

The association between the exposure and bioaccumulation of endocrine disruptor chemicals (EDCs) and their adverse effects on human and wildlife populations has raised concern worldwide. Regulatory agencies such as the Environmental Protection Agency (EPA) and the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) in the United States; the European Commission for the Validation of Alternative Methods (ECVAM) in the European Union; and the Japanese Commission for the Validation of Alternative Methods (JaCVAM) in Japan have conducted studies to validate new test methods for EDCs.^{1, 2} This concern has also reached producers such as the Campbell Soup Company, which is phasing bisphenol A (BPA) out of its product containers.³