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Recent in In vitro (page 6 of 6)

Rapid Colorimetric Analysis of para-Phenylenediamine in Henna-based, Non-permanent Tattoo Color Mixtures

In some henna mixtures, para-phenylenediamine (PPD) has illegally been added and it is responsible for complications such as allergic contact dermatitis. While high-performance liquid chromatography has previously been used to detect PPD, a colorimetric method that is faster and portable, described here, has been developed. For product developers, this method can be used to evaluate henna plant extracts.

P&G Presents 'Omics' Findings in Acne, Male Grooming, Dandruff and Anti-aging

During the World Congress of Dermatology, Procter & Gamble Beauty and Grooming is presenting new findings in acne, male grooming, dandruff and anti-aging based on a broader "omics"—i.e., genomics, proteomics and metabolomics, research tool.

ICCVAM and NICEATM Hold Meeting on Endocrine Disruptor Test Method

ICCVAM and NICEATM will hold a peer review meeting on March 29-30, 2011, for an in vitro test method that determines if chemicals are endocrine disruptors.

A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

ISO Equips Formulators to Identify Low-risk Cosmetic Products

The International Organization for Standardization (ISO) has released an international standard that will assist the cosmetic industry in identifying those products that have a low potential for contamination.

Fluorescence Laser Scanning Confocal Microscopy to Assess the Penetration of Low Molecular Protein Hydrolyzates Into Hair

The present study uses confocal laser scanning fluorescence microscopy to assess the penetration of protein hydrolyzates into hair. While higher amounts of protein were found in the cuticle, still significant quantities were observed in the cortical parts of hair, and this penetration was enhanced by longer incubation times.

Paper Posted to Aid Manufacturers with Harmonized Microbial Testing

Microtest Laboratories has posted a white paper on its website to help personal care product manufacturers understand microbial limits testing policies in accordance with the harmonization of the United States Pharmacopeia (USP), European Pharmacopeia (EP) and Japanese Pharmacopeia (JP) requirements.

ICCVAM Recommends Ocular Safety Tests for Cosmetics and Other Products

Four test method evaluation reports are now available from ICCVAM that provide recommendations for performing eye safety testing more humanely, and for developing and using non-animal test methods and strategies. Among these reports, ICVAAM has recommended that a cytosensor microphysiometer (CM) test method may be used to screen surfactant-containing formulations such as personal care products for the ability to cause permanent or severe eye injuries.

Antiaging in a Different Light: Assessing How Chromophores Color Perception

Aging influences cutaneous parameters that give rise to progressive changes in three skin chromophores, altering the visual homogeneity of skin. To address these changes, the authors developed and examined the effects of a complex based on Siegesbeckia orientalis and Rabdosia rubescens using a novel skin imaging technique.

TRI/Princeton Offers Hair Benchmarking Study to Share Testing Costs

This benchmarking study allows manufacturers to test hair products for conditioning, anti-breakage strengthening, and anti-static flyaway reduction with shared controls and labor to reduce costs by up to 57%. The company is accepting participants until Aug. 15, 2010.

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