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512 Results
Type: Article
Actives
A Compound to Increase Natural CoQ10 for Anti-aging Benefits
Oxidative stress is a major factor in skin aging, thus a topical compound was designed to increase anti-oxidant coenzyme Q10 (CoQ10) within the body. Described here are in vivo and in vitro studies assessing the compound’s antioxidant and anti-aging capabilities. Results indicate that the modulation of intracellular CoQ10 and its binding proteins appears to protect skin from oxidative damage.
Cleansing
Comparatively Speaking: The INCI Names vs. Properties of Silicone Surfactants
Surface tension is a ruling factor in the formulator's world. In this edition of "Comparatively Speaking," Tony O'Lenick explains its influence on foam and wetting; he also demonstrates how little the INCI name reveals about a material's properties.
Method/Process
Scale-up Success: Untapping the Potential of Computational Fluid Dynamics
Scaling up cosmetic products to manufacturing facilities is a common cause of formulation difficulties. Computational fluid dynamics offer a means to model and troubleshoot potential problems in advance, and could become a standard tool to reduce production costs.
Cleansing
Comparatively Speaking: CAPB from Coconut Oil vs. Fatty Acid
Anthony J. O'Lenick, Jr., explains that CAPB can be made from two different processes, one with coconut oil and the other with fatty acid, which create two potential differences that affect how the material works in a formulation.
Colorant
X-Free Nail Polish: Scientific Evidence and Market Reality, A Commentary
This commentary reviews claims and scientific evidence for hazards associated with ingredients omitted from nail polishes and marketed as such. It aims to arm product developers with both the scientific evidence and market reality, and envisions a time when both sides can meet in the middle.
Magazine
Reclaiming Skin Clarity: Upcycled
Pinus Strobus
Bark for a Healthy Complexion
Eastern white pine bark contains bioactive molecules with potential skin benefits. These can be sourced via upcycling to support a circular economy. An upcycled extract thereof was formulated in creams and tested for effects on skin clarity and more.
Anti-aging/Face
Communicating Anti-aging Skin Care Benefits to the Consumer: Part II
This dialogue, the second of a two-part series, is based on a presentation given by Katerina Steventon, PhD, (KS) at the Anti-Ageing Skin Care Conference on June 12, 2012 in London. It establishes a conversation with Steve Barton (SB), a skin biologist, to discuss concerns and perceptions of British consumers related to skin care. Barton has extensive experience working with marketing teams to improve communication of skin care benefits to consumers by initiating communication between the consumer and the formulator.
Literature/Data
Comparatively Speaking: Wetting/Eye Irritation in Trisiloxane vs. Dimethicone Copolyol
In a previous "Comparatively Speaking" column, Tony O'Lenick explained the differences between trisiloxane and dimethicone copolyol in terms of surface tension. Here he explains the differences in terms of wetting and eye irritation.
Regional
European Regulatory Update: Cosmetic Ingredient Changes Coming in 2025-2026
This article looks to changes in 2025-2026 to the status of ingredients in the EU and UK. Examples include nanomaterial and UV filter bans/restrictions, limits on actives, labeling formaldehyde-releasing preservatives and allergens, ecodesign and others.
Actives
Mangixyl™, the microbiome-friendly sebum harmoniser for all skin complexions
Givaudan Active Beauty unveils Mangixyl™, a powerful microbiome-friendly cosmetic ingredient for all skin complexions with proven efficacy targeting oily skin through sebum regulation, created from mango leaves, responsibly sourced in Burkina Faso.
Literature/Data
Comparatively Speaking: EFAs in Pharma vs. Cosmetics and COVID-19 Potential
In this Comparatively Speaking, Tony O’Lenick presents an edited excerpt from an article in
Inform
relating materials well-known by cosmetic chemists: essential fatty acids (EFAs). Highlighted here is their novel bioactivity in relation to COVID-19.
Regional
Massive Innovations, Complex Regulations: The Entanglements of Hair Care Products
Few relationships are as volatile as the one we share with our hair. Either we have too much of it or too little; we grow it where we don’t want it and lose it where we do. Regardless of each individual case, hair growth and removal spawns all kinds of new technology, and along with it, new regulations.
Methods/Tools
Storage Studies of Preservative Solutions in Commonly Used Plastic Containers
In an interesting article published in this journal recently, Armstrong reviewed work done on the uptake of preservatives by plastic packaging materials, a subject of importance to both the pharmaceutical and cosmetic industries.
Actives
A DNA Repair Complex to Decrease Erythema and UV-induced CPD Formation
The authors describe how a DNA-repair complex based on amino acids decreases UV-induced DNA damage in reconstituted human skin and reduces related skin inflammation in human volunteers.
Actives
A DNA Repair Complex to Decrease Erythema and UV-induced CPD Formation
The authors describe how a DNA-repair complex based on amino acids decreases UV-induced DNA damage in reconstituted human skin and reduces related skin inflammation in human volunteers.
Literature/Data
Comparatively Speaking: Naturally Occurring vs. Naturally Derived vs. Chemically Modified Butters
Tony O'Lenick explains the difference between naturally occurring, naturally derived and chemically modified butters since some butters possess better cosmetic properties, which is of use to the formulator.
Hair Care
ProRenew Complex CLR™ has high efficacy for postbiotic scalp care
A new study proves that ProRenew Complex CLR™ has a profound and perceivable effect on the scalp, even from a rinse-off formulation.
Tech/Equipment/Services
Stroke of Genius: Successive Combing Force Yields Realistic Conditioning Results
Combing tests are widely used to characterize the conditioning performance of products at one snapshot in time. A successive combing force device was designed to more realistically simulate the entire shampooing and conditioning process. Here, the authors put it to the test.
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