A DNA Repair Complex to Decrease Erythema and UV-induced CPD Formation

Oct 4th, 2013

Giorgio Dell’Acqua, Dellacqua Consulting and Kuno Schweikert, Induchem AG

Solar radiation such as UVA and UVB induces physiological damage in the skin. Photoaging is a classic example of UV-induced wrinkle formation and thinning of the skin. This phenotype change reflects a deeper impact at the molecular level, in particular on the DNA double helix present in each cell nucleus. The cumulative effect of repeated damage strongly contributes to the development of DNA mutations and down-regulates proteins essential to maintain normal skin turnover.

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