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43 Results

Section: Testing > Safety/Stability

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Why the FDA's 'Sunscreens in the Bloodstream' Study is Flawed

A recent study published in the Journal of the American Medical Association tested the potential systemic absorption of certain sunscreens. Results identified their presence in subjects' bloodstreams; however, as industry expert David Steinberg explains, the study is misleading and fails to consider crucial variables.

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When the Dust Settles: Keratinocyte Differentiation is the Anti-pollution Solution

This article describes in vitro, ex vivo and in vivo models to examine the effects of PM in skin, with particular interest in a botanical extract to mitigate the described effects. Urban pollution including particulate matter (PM) can affect the skin barrier by inducing numerous cell stresses.

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Getting the Breakdown: Testing the Biodegradation and Styling Performance of Polyurethane Film Formers

Personal care products end their life cycles in water, where poor biodegradability can be concerning. This study compares the biodegradability and hair-styling performance of polyurethane, polyacrylates and polyvinylpyrrolidone film formers.

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Toxicity Testing: Read Between the Lines

Active ingredients aren't thinkers, they're do-ers. But can they do too much? As explored during in-cosmetics 2017, in an industry permeated with astounding product claims, it becomes all the more crucial to test for potential toxic effects and really understand those results.

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[podcast] The Next-generation Retinoid

Retinol has proven anti-aging benefits, but also drawbacks. However, according to Tom Mammone, Ph.D., of The Estée Lauder Cos. and Clinique Labs, a new retinoid ester could bridge this divide. Listen now!

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Bee Venom is Back in the Buzz

Bee venom is back, this time with data. According to a thesis from the University of Strathclyde, previous reports of its effects were anecdotal and incomplete. Now there's science backing it; especially in terms of safety.

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Letter to the Editor: Resorcinol Clarification

Please take note of this concerned reader's comment, as Cosmetics & Toiletries and Global Cosmetic Industry do not wish to propagate false or misleading information to the cosmetic community.

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The New Bionic Reality: Imprinted Wearables

New dimensions in 3D printing are now possible thanks to a novel process developed at the University of Minnesota. Not only could this give surgical robots the sense of touch, it could embed the human skin with biometric monitoring capabilities.

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Photostability Leads the Way: Formulating Safer Sunscreens

The need to prevent skin from UV damage is well-understood but the most effective way to achieve this is not. Here, a novel photostabilizer is presented in a test pump sunscreen spray formula as part of a total photoprotection strategy.

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Tox Testing at the Speed of Light (Really)

Until now, testing chemicals for their toxicity has relied on reporter genes, which can take 24 hr to deliver results. A new approach from North Carolina State University, however, uses a modified protein that emits light when binding occurs—effectively signaling its safety.

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Here Comes the Sun Protection: ISO Test Methods

Our knowledge of the sun and its effects on skin has increased over the years, including the damaging effects of UVA and UVB light. Testing methods for UVA and UVB rays differ; the following is a review of the testing protocols of the European Union and United Kingdom. (Click through to the Digital Edition)

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3 Skin Sensitization Tests to Meet the EU Mandate

The EU Cosmetics Regulation requires skin sensitization to be determined through non-animal methods. Here, the pathways for skin sensitization are reviewed, three non-animal tests are described in brief, and their combination with one another, followed by human assessment, are explored.

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Testing the Fate (and Exposure) of Cosmetic Ingredients

Risk and exposure go hand-in-hand. So when researchers dared to publish a new method to assess the exposure and fate of cosmetic ingredients, we couldn't help but give them exposure, in this review.

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10 Aspects of Cosmetics Data Mandated by the EU

Product safety: It's crucial. That's why European Regulation (EC) No. 1223/2009 requires the following 10 aspects of cosmetic product data to be provided in order to support a proper safety assessment.

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PCPC's Beth Jonas Defends Cosmetic Science to the U.S. Senate

It's nice to see our government liaison supporting our scientists' efforts by standing up to share with others the notion that cosmetic science is real.

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Lab Lessons—Wise Words from the Bench with Mark Chandler

Cosmetics & Toiletries presents “Lab Lessons,” featuring interviews with veteran members of the personal care industry to share practical advice from the lessons they have learned.

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Cosmetovigilance and Safety Assessment in the World of Active Ingredients

It can be deduced from today's scientific literature that countless ingredients have been developed with the intent to alter the structure and function of human skin. This raises important questions in terms of how these products should be regulated and what types of safety standards they should be held to.

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China to Accept Animal-alternative Test Data Under These Conditions

Could the animal testing mandate for cosmetics be over in China? No. At least not yet. But under given circumstances, animal-alternative test data will instead be allowed, as well as abstracts of safety assessments.

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