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Section: Testing > Method/Process

Quantifying the Performance of Hair Styling Products—Part 1

There are two general classifications of hair styling products—those that help with style creation and those that prolong the style. Both facilitating style creation and promoting hold longevity stem from the presence of water-soluble polymers in formulations. This paper discusses methods to evaluate these properties and quantify performance.

A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

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Gattefossé and Ambiotis Uncover Inflamm'aging Insights

Inflammation is a natural defense but when left unresolved, it can negatively impact the skin and contribute to aging. Gattefossé and Ambiotis teamed up to explore these mechanisms.

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Screening Botanical Ingredients: Challenges and Opportunities

Botanical ingredients are interesting for their unique and complementary chemical diversities yet they are criticized for these very traits, which make quality assurance, reproducibility and good phytochemical characterization—required for successful high throughput screening, difficult. This article discusses these challenges as well as the benefits of large-scale screenings of botanical extracts that are currently used or developed for cosmetic product development.

In Vitro Model for Decontamination of Human Skin

The present study utilized an in vitro model to compare the decontamination capacity of three model decontaminant solutions: tap water, isotonic saline and hypertonic saline. Human cadaver skin samples were dosed with radio-labeled [14C]-formaldehyde and the surface skin of each sample was washed after each exposure with one of the three model decontaminant solutions.

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A Review of Genomic Techniques in Cosmetics Testing

Genomics assists product developers in understanding the expression of specific genes and their relationship to particular skin attributes. This article reviews commonly used testing techniques, such as DNA microarray, RT-PCR, SAGE, northern blot and RNA sequencing, and describes their application in testing the effects of cosmetic ingredients and products on skin.

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[video] Understanding Adhesion of Pollution Particles to Skin

University of Le Havre researchers sought to better understand the adhesion mechanism of pollution particles to skin. Here, Lívia Salomao Calixto, Ph.D., explains their study design and findings, presented at the IFSCC Conference in Milano.

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Beating the Damaging Effects of Heat on Hair

Heat treatments are among the more popular methods for achieving straight hair, yet their high temperatures are quite damaging to the hair’s structures. Learn about the damaging effects and suggested solutions for repairing heat-damaged hair.

Device for Measuring Nanoparticles and Proteins

Malvern Instuments has launched a device suitable for the characterization of proteins and nanoparticles where the highest sensitivity for size and zeta potential measurement is required.

AMS Revolutionizes Absorption and Metabolism Studies

Quantification of percutaneous penetration and metabolism of skin care ingredients has seemed daunting; however, new technology provides a ready solution for the problematic arena. Accelerator mass spectrometry (AMS) is a new analytical method that measures a biological response better than the existing technique.

Cosmetic Testing in 2000 and Beyond

Changes in cosmetic testing are being driven by regulation and advanced technologies, such as new in vitro methods, molecular combinational chemistry and skin delivery. Part of the Series: From Test to Claim.

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Acquisition Expands DSM and Amyris Partnership

Global science-based company active in health, nutrition and materials, DSM formed a strategic alliance in May 2017 with Amyris, Inc., an industrial bioscience company. The two are now collaborating on expanding with several significant product development collaborations including the acquisition of specialty production facilities.

The model accurately predicted skin permeability and the speed of the UHPLC method could classify it as a high-throughput approach.

Test Model Developed to Predict Skin Permeability of Compounds

A test model published in the Journal of Chromatography A uses retention on octadecyl, cholesterol-bonded and immobilized artificial membrane columns to accurately predict the skin permeability of compounds.

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LVMH Proves: Age Really is a State of Mind

During the IFSCC 2016 Congress, LVMH researcher Héloise Vergnaud presented her company's work on skin sagging and panelist reactions and emotional associations to it. Her results show how age really is a mindset.

In vivo Quantification of Corneocyte Lipids by Image Analysis

In a new method described here by the authors, fluorescence emitted from samples and captured by image analysis is used to quantify the number of lipids present in the cornified cell envelope. This in vivo approach is fast and noninvasive and could be used to screen molecules for potential moisturizing and restructuring effects.

Tape Stripping Method in Humans: Comparison of Evaporimetric Methods

The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.

Modeling UVB-induced Formation of Photoproducts in Human Keratinocytes

The authors describe a model to visualize the appearance of cyclobutane-pyrimidine dimers in the nuclei of normal human keratinocytes after UV irradiation. These dimers are one of the principal agents in DNA damage. The model can be used to assess the effect of a cosmetic ingredient on the formation of direct UV-induced lesions to DNA.

A Laboratory Method for Measuring the Water Resistance of Sunscreens

A new laboratory in vitro method for the measurement of sunscreen water resistance uses spectrophotometric analysis of a model skin substitute before and after 80-minute immersion. It gives good correlation with the FDA’s 80-minute immersion SPF results (very water resistant). The method is especially good for screening new formulations or water-resistant technologies.

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