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Type: Article

Section: Testing > Method/Process

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Propanediol Caprylate: Shifting the Microbiome, Sebum Levels and Classic Approach to Dandruff

Propanediol caprylate was previously shown to deactivate Malassezia for dandruff control. In parallel, its effects to shift the balance of Cutibacterium and Staphylococcus in the scalp microbiome, and reduce dandruff and sebum are explored here.

Compass—Affinity to Water

While our path may appear to veer far from water, its status as the universal solvent will bring us back to the source.

Compass: Direct Routes

Will a flourishing category ever chance revealing this truth behind naturals to consumers? Perhaps so, as the naturals market becomes more saturated and key manufacturers seek ways to drive consumer interest into new areas.

Computer-aided Formulating

Informatics techniques have been developed that are capable of manipulating huge data sets that underpin modern formulation—from mining for information, to analyzing vast amounts of data. This article highlights how the use of computer technology can increase the efficiency and efficacy of formulating.

Compass—Best Foot Forward

From an insider’s view, safety testing is an assumed step in the development of any product on the market. This puts the pressure on analytical and quality control efforts behind the scenes to ensure that ingredients and products meet or exceed expectations. In doing so, theoretically, no one else has to give it a second thought. For those who must give it considerable thought, this edition features two articles on testing, among other topics.

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Scale-up Success Requires Compromise

The in-cosmetics Global technical session on scale-up success was, in and of itself, a scale-up success as it left standing room only for a crowd of attendees eager to learn tips, tricks and best practices.

In Sight—QOL Testing: Complementing Clinicals

Personal care efficacy tests are known to test the physical effects or toxicity of products, often omitting more abstract and possibly equally as important factors such as well-being.

In Sight—QOL Testing: Complementing Clinicals

Personal care efficacy tests are known to test the physical effects or toxicity of products, often omitting more abstract and possibly equally as important factors such as well-being.

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Comparatively Speaking: Crossmodal vs. Lineal Perception

Lineal perception relates to a direct line between a stimuli and a single sensory interpretation. Crossmodal perception refers to responses and interpretations of various senses to a stimulus, offering product developers opportunities to create novel consumer experiences.

Computerized Measurement and Correction of Color Cosmetics

With a spectrophotometer and computerized color measurement software, the cosmetic chemist can do both basic color quality control and color formulation and correction easily in the lab.

Green Formulations: Not All Components Are Equal

In the consumer’s mind, a natural or green cosmetic is automatically safe; however, the safety, quality and efficacy of botanical ingredients used in formulations need to be carefully assessed. Stability is also an important issue. Current research is directing analyses of final formulations to evaluate not only their cosmetic raw materials, but also their active materials.

Green Formulations: Not All Components Are Equal

In the consumer’s mind, a natural or green cosmetic is automatically safe; however, the safety, quality and efficacy of botanical ingredients used in formulations need to be carefully assessed. Stability is also an important issue. Current research is directing analyses of final formulations to evaluate not only their cosmetic raw materials, but also their active materials.

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Comparatively Speaking: Gene vs. Protein Expression Studies

What is the difference between gene and protein expression studies to evaluate the efficacy of cosmetic products? Nava Dayan, Ph.D., explains in this edition of "Comparatively Speaking."

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Comparatively Speaking: Standard vs. Quantum-level Research

If you've ever conducted an experiment and could not explain the results, it could be due to hidden variables. This leads to what's referred to as quantum-level research, which is described by Nava Dayan, Ph.D., in this edition of "Comparatively Speaking."

Biomimetic vs. Traditional Skin Moisturization: An In vivo Comparison*

To alleviate skin dryness, humectants and occlusive substances are traditionally used, mostly in combination. A third, relatively recent approach is biomimetic, i.e., active ingredients with lamellar structure containing skin-identical lipids. The aim of this study was to determine whether a biomimetic cream could deliver superior moisturization to human volunteers, compared with a conventional moisturizer containing petrolatum and mineral oil.

Tape Stripping Method in Humans: Comparison of Evaporimetric Methods

The current preliminary study compared the sensitivity and correlation of open chamber device and closed chamber device on a tape stripping human model. The amount of SC removed by tape stripping was also quantified with a protein assay method.

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Q&A: How Do Conventional and Accelerated Preservative Tests Compare?

"How do accelerated and conventional preservative testing compare? What can each measure?" This reader inquiry led us to John Yablonski, of BioControl, who provided the following answer.

Comparing Methods to Measure Porcine Skin Integrity In Vitro

To confirm the integrity of porcine ski prior to penetration tests, published studies show that measuring transepidermal water loss, transdermal electrical resistance or caffeine penetration levels are often chosen techniques. New results demonstrate that

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