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Patent Pick: Stem Cell Derivative to Take the Lead in K-beauty

Contact Author Rachel Grabenhofer, Cosmetics & Toiletries
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Active. Stimulating. Expressive. Sounds like a review from a Broadway performance but it's not; it's the latest skin-whitening, tissue-repairing, stem cell-derived cosmetic active out of Korea.

Stem cell-derived exosome to regenerate adipose tissue, whiten skin or improve wrinkles 
WIPO Patent Application WO/2016/072821
Publication date: May 12, 2016
Assignee: Industry-University Cooperation Foundation, Hanyang University Erica Campus, Korea

Described in this patent application is a composition that induces adipocyte differentiation and/or adipose tissue regeneration. The active ingredient is an exosome extracted from a stem cell differentiating into an adipocyte, which expresses bioactive factors at a strong rate.

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The exosome contains genes, proteins and growth factors associated with the proliferation, differentiation and regeneration of stem cells. It can therefore be applied to differentiation-inducing agents in stem cells, injections for tissue regeneration, fillers for cosmetic purposes, preparations for tissue engineering, etc. 

The described ingredient is purified and does not include antibiotics, serums or culture solution. It also is a cell-derived lipid transporter and imparts skin-whitening, wrinkle-reducing, skin-regeneration and scar-improvement functions.

Patent application accessed May 24, 2016.

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